CHAPTER 1 BEDROOM BASICS: HOW AN ERECTION HAPPENS
1 G. J. Christ and T. Lue, “Physiology and Biochemistry of Erections,” Endocrine 23, nos. 2 and 3 (2004): 93–100.
2 M. Bitsch, B. Kromann-Andersen, J. Schou, and E. Sjontoft, “The Elasticity and the Tensile Strength of Tunica Albuginea of the Corpora Cavernosa,” Journal of Urology 143, no. 3 (1990): 642–5.
3 K. E. Andersson and G. Wagner, “Physiology of Penile Erection,” Physiological Reviews 75, no. 1 (1995): 191–236.
4 I. Saenz de Tejada et al., “Physiology of Erectile Function,” The Journal of Sexual Medicine 1, no. 3 (2004): 254–65.
5 Ibid.
6 G. J. Christ and T. Lue, “Physiology and Biochemistry of Erections,” Endocrine 23, nos. 2 and 3 (2004): 93–100.
7 L. J. Ignarro et al., “Nitric Oxide and Cyclic GMP Formation upon Electrical Field Stimulation Cause Relaxation of Corpus Cavernosum Smooth Muscle,” Biochemical and Biophysical Research Communications 170, no. 2 (1990): 843–50.
8 W. D. Steers, “Pathways and Central Sites Involved in Penile Erection: Neuroanatomy and Clinical Implications,” Neuroscience & Biobehavioral Reviews 24, no. 5 (2000): 507–16.
9 F. Giuliano and O. Rampin, “Neural Control of Erection,” Physiology and Behavior 83, no. 2 (2004): 189–201.
10 A. Argiolas and M. R. Melis, “Oxytocin-Induced Penile Erection. Role of Nitric Oxide,” Advances in Experimental Medicine and Biology 395 (1995): 247–54.
11 R. G. Paredes and M. J. Baum, “Role of the Medial Preopticarea/Anterior Hypothalamus in the Control of Masculine Sexual Behavior,” Annual Review of Sex Research 8 (1997): 68–101.
12 K. E. Andersson, “Neurophysiology/Pharmacology of Erection,” International Journal of Impotence Research 13, sup. 3 (2001): S8–17.
13 A. D. Baird et al., “Neurological Control of Human Sexual Behaviour: Insights from Lesion Studies,” Journal of Neurology, Neurosurgery, and Psychiatry 78 (2007): 1042–1049.
CHAPTER 2 COME AND GET IT: EJACULATION AND ORGASM
1 Vincent Puppo and Giulia Puppo, “Comprehensive Review of the Anatomy and Physiology of Male Ejaculation: Premature Ejaculation Is Not a Disease,” Clinical Anatomy 29, no. 1 (January 2016): 111–19.
2 Pierre Clement and Francois Giuliano, “Physiology and Pharmacology of Ejaculation,” Basic & Clinical Pharmacology & Toxicology 119 (2016): 18–25.
3 Puppo and Puppo, “Comprehensive Review of the Anatomy and Physiology of Male Ejaculation,” 111–19.
4 Clement and Giuliano, “Physiology and Pharmacology of Ejaculation,” 18–25.
5 David Rowland, Chris G. McMahon, Carmita Abdo, Juza Chen, Emmanuele Jannini, Marcel D. Waldinger, and Tai Young Ahn, “Disorders of Orgasm and Ejaculation in Men,” Journal of Sexual Medicine 7 (2010): 1668–86.
6 Ibid.
7 O. Dhangirian and A. Spitz, “Role of the Epididymis in Sperm Maturation,” BJUI (January 2016): 10.18591/BJUIK.0509.
8 Puppo and Puppo.
9 Clement and Giuliano.
10 Puppo and Puppo.
11 Clement and Giuliano.
12 Puppo and Puppo.
13 M. D. Waldinger, P. Quinn, M. Dilleen, R. Mundayat, D. H. Schweitzer, and M. Boolell, “A Multinational Population Survey of Intravaginal Ejaculation Latency Time,” Journal of Sexual Medicine 2 (2005): 492–7.
14 H. Porst, F. Montorsi, R. C. Rosen, L. Gaynor, S. Grupe, and J. Alexander, “The Premature Ejaculation Prevalence and Attitudes (PEPA) Survey: Prevalence, Comorbidities, and Professional Help-Seeking,” European Urology 51(2007): 816–23.
15 M. D. Waldinger, “The Neurobiological Approach to Premature Ejaculation,” Journal of Urology 168 (2002): 2359–67.
16 M. D. Waldinger and B. Olivier, “Animal Models of Premature and Retarded Ejaculation,” World Journal of Urology 23 (2005): 115–18.
17 Antonio L. Pastore and Giovanni Palleschi, “Pelvic Floor Muscle Rehabilitation for Patients with Lifelong Premature Ejaculation: A Novel Therapeutic Approach,” Therapeutic Advances in Urology 6, no. 3 (2014): 83–88.
18 W. H. Masters and V. E. Johnson, Human Sexual Inadequacy (London: Churchill, 1970), xi–467.
19 J. H. Semans, “Premature Ejaculation: A New Approach,” Southern Medical Journal 49, no. 4 (1956): 353–58.
20 D. H. Shin and A. Spitz, “The Evaluation and Treatment of Delayed Ejaculation,” Sexual Medicine Reviews 2, nos. 3 and 4 (October 2014): 121-133. doi: 10.1002/smrj.25. Epub 2015 Oct 19.
21 Christian J. Nelson, Absaar Ahmed, Rolando Valenzuela, Marilyn Parker, and John P. Mulhall, “Assessment of Penile Vibratory Stimulation as a Management Strategy in Men with Secondary Retarded Orgasm,” Urology 69 (2007): 552–56.
22 R. Keller and F. Mongini, “Switch to Quetiapine in Antipsychotic Agent-Related Hyperprolactinemia,” Neurological Sciences 23, no. 5 (2002): 233–35.
23 Michael J. Butcher and Robert E. Brannigan, “Ejaculatory Disorders,” in T. S. Köhler and K. T. McVary (eds.), Contemporary Treatment of Erectile Dysfunction (Switzerland: Springer International Publishing, 2016), 345.
24 C. T. Li, T. P. Su, J. C. Hsieh, and S. T. Ho, “Cabergoline for the Treatment of Male Anorgasmia.” Paper presented at the American Urological Association Annual Meeting, 2012.
25 M. Safarinejad, “Midodrine for the Treatment of Organic Anejaculation but Not Spinal Cord Injury: A Prospective Randomized Placebo-Controlled Double-Blind Clinical Study,” International Journal of Impotence Research 21 (2009): 213–20.
CHAPTER 3 BIG GULP: A TASTEFUL REVIEW OF SEMEN
1 http://jezebel.com/a-complete-breakdown-of-the-nutritional-content-of-semen-953356816, which references Derek H. Owen and David F. Katz, “A Review of the Physical and Chemical Properties of Human Semen and the Formulation of a Semen Simulant,” Journal of Andrology 26, no. 4 (July/August 2005).
2 file:///Users/aaronspitz/Documents/penis%20book/references%20and%20notes%20ideas/semen%20taste/Evolutionary%20psychology_%20the%20adaptive%20significance%20of%20semen%20flavor%20%C2%AB%20Why%20Evolution%20Is%20True.xhtml.
3 http://www.increasespermvolume.com/how-to-make-semen-taste-better/.
4 file:///Users/aaronspitz/Documents/penis%20book/references%20and%20notes%20ideas/semen%20taste/Evolutionary%20psychology_%20the%20adaptive%20significance %20of%20semen%20flavor%20%C2%AB%20Why%20Evolution%20Is%20True.xhtml.
5 Carin A. Koelman and Audrey B. Coumans, “Correlation between Oral Sex and a Low Incidence of Preeclampsia: A Role for Soluble HLA in Seminal Fluid?” Journal of Reproductive Immunology 46, no. 2 (March 2000): 155–66.
6 http://www.slate.com/articles/health_and_science/science/2012/07/morning_sickness_can_more_sex_help_.html.
7 Gordon G. Gallup, Rebecca L. Burch, and Steven M. Platek, “Does Semen Have Antidepressant Properties?” Archives of Sexual Behavior 31, no. 3 (June 2002): 289–93.
CHAPTER 4 SIZE MATTERS: HOW DO YOU MEASURE UP?
1 H. Wessells, T. F. Lue, and J. W. McAninch, “Penile Length in the Flaccid and Erect States: Guidelines for Penile Augmentation,” Journal of Urology 156 (1996): 995–97.
2 Y. Aslan, A. Atan, O. Aydın, V. Nalçacıoğlu, A. Tuncel, and A. Kadıoğlu, “Penile Length and Somatometric Parameters: A Study in Healthy Young Turkish Men,” Asian Journal of Andrology 13 (2011): 339–41.
3 R. Ponchiette, N. Mondaini, M. Bonaf, F. Di Loro, S. Biscioni, and L. Masieri, “Penile Length and Circumference: A Study on 3,300 Young Italian Males,” European Urology 39 (2001): 183–86.
4 K. Promodu, K. Shanmughadas, S. Bhat, and K. Nair, “Penile Length and Circumference: An Indian Study,” International Journal of Impotence Research 19 (2007): 558–63.
5 K. Siminoski and J. Bain, “The Relationships among Height, Penile Length, and Foot Size,” Annals of Sex Research 6 (1993): 231–35.
6 D. Mehraban, M. Salehi, and F. Zayeri, “Penile Size and Somatometric Parameters among Iranian Normal Adult Men,” International Journal of Impotence Research 19 (2006): 303–9.
7 J. P. Rushton, Race, Evolution and Behavior, 3rd ed. (Port Huron, MI: Charles Darwin Research Institute, 2000).
8 D. Veale, S. Miles, et al., “Am I Normal? A Systematic Review and Construction of Nomograms for Flaccid and Erect Penis Length and Circumference in Up to 15,521 Men,” BJU International 115 (2015): 978–86.
9 D. Herbenick, M. Reece, V. Schick, and S. A. Sanders, “Erect Penile Length and Circumference Dimensions of 1,661 Sexually Active Men in the United States,” Journal of Sexual Medicine 11 (2014): 93–101.
10 K. R. Wylie and I. Eardley, “Penile Size and the ‘Small Penis Syndrome,’” BJU International 99 (2007): 1449–55.
11 D. Veale, A. Boocock, K. Gournay, et al., “Body Dysmorphic Disorder. A Survey of Fifty Cases,” British Journal of Psychiatry 169 (1996): 196–201.
12 Wessells, Lue, and McAninch, “Penile Length in the Flaccid and Erect States.”
13 Veale, Miles, et al., “Am I Normal?”
14 W. Lim et al., “Dietary Cholesterol Affects Expression of Prostatic Acid Phosphatase in Reproductive Organs of Male Rats,” Biochemical and Biophysical Research Communications 456 (2015): 421–27.
15 J. Lever, D. A. Frederick, and L. A. Peplau, “Does Size Matter? Men’s and Women’s Views on Penis Size across the Lifespan,” Psychology of Men & Masculinity 7 (2006): 129–43.
16 J. Lloyd, N. Crouch, et al., “Female Genital Appearance: ‘Normality’ Unfolds,” BJOG: An International Journal of Obstetrics and Gynaecology 112 (May 2005): 643–46.
17 A. Webber and M. Walters, “Vaginal Anatomy and Sexual Function,” Obstetrics and Gynecology 86, no. 6 (December 1996): 946–49.
18 R. Eisenman, “Penis Size: Survey of Female Perceptions of Sexual Satisfaction,” BMC Women’s Health 1 (2001). doi: 10.1186/472-6874-1-1.
19 N. Mondaini and R. Ponchiette, “Penile Length Is Normal in Most Men Seeking Penile Lengthening Procedures,” International Journal of Impotence Research 170, no. 3 (2002): 1057-58.
20 R. Shamloul, “Treatment of Men Complaining of Short Penis,” Urology 65, no. 6 (2005): 1183–85. PubMed: 15922413.
21 H. Ghanem, R. Shamloul, F. Khodeir, H. ElShafie, A. Kaddah, and I. Ismail, “Structured Management and Counseling for Patients with a Complaint of a Small Penis,” Journal of Sexual Medicine 4, no. 5 (2007): 1322–27. PubMed: 17419818.
CHAPTER 5 BIGGER HARDER FASTER: PENIS ENHANCEMENTS
1 N. Campbell, J. Clark, V. Stecher, J. Thomas, A. Callanan, B. Donnelly, I. Goldstein, and J. Kaminetsky, “Adulteration of Purported Herbal and Natural Sexual Performance Enhancement Dietary Supplements with Synthetic Phosphodiesterase Type 5 Inhibitors,” Journal of Sexual Medicine 10 (2013): 1842–49.
2 S. Newmaster, M. Grguric, D. Shanmughanandhan, S. Ramalingam, and S. Ragupathy, “DNA Bar Coding Detects Contamination and Substitution in North American Herbal Products,” BMC Medicine 11 (2013): 222.
3 D. Jang, M. Lee, S. Byung-Cheul, and E. Ernst, “Red Ginseng for Treating Erectile Dysfunction: A Systematic Review,” British Journal of Clinical Pharmacology 66 (2008): 444–50.
4 B. Hong, Y. Ji, J. Hong, K. Nam, and T. Ahn, “A Double-Blind Crossover Study Evaluating the Efficacy of Korean Red Ginseng in Patients with Erectile Dysfunction: A Preliminary Report,” Journal of Urology 168 (2002): 2070–73.
5 http://www.webmd.com/men/horny-goat-weed-epimedium#1.
6 J. Melnyk and M. Marcone, “Aphrodisiacs from Plant and Animal Sources—a Review of Current Scientific Literature,” Food Research International 44 (2011): 840–50.
7 Jonathan Israel and Eric L. Laborde, “Alternative and Internet Drugs that Affect Sexual Function,” in T. S. Köhler and K.T. McVary (eds.), Contemporary Treatment of Erectile Dysfunction (Switzerland: Springer International Publishing, 2016), 141.
8 Melnyk and Marcone, “Aphrodisiacs from Plant and Animal Sources.”
9 Israel and Laborde, “Alternative and Internet Drugs that Affect Sexual Function.”
10 G. Gonzales, A. Cordova, K. Vega, A. Chung, A. Villena, C. Gonez, and S. Castillo, “Effect of Lepidium meyenii (MACA) on Sexual Desire and Its Absent Relationship with Serum Testosterone Levels in Adult Healthy Men,” Andrologia 34 (2002): 367–72.
11 T. Zenico, A. Cicero, L. Valmorri, M. Mercuriali, and E. Bercovich, “Subjective Effects of Lepidium meyenii Extract on Well-Being and Sexual Performances in Patients with Mild Erectile Dysfunction: A Randomised, Double-Blind Clinical Trial,” Andrologia 41 (2009): 95–99.
12 N. Brooks, G. Wilcox, K. Walker, J. Ashton, M. Cox, and L. Stojanovska, “Beneficial Effects of Lepidium meyenii (Maca) on Psychological Symptoms and Measures of Sexual Dysfunction in Postmenopausal Women Are Not Related to Estrogen or Androgen Content,” Menopause 15 (2008): 1157–62.
13 Israel and Laborde, 143.
14 Gustavo F. Gonzales and Cynthia Gonzales-Castañeda, “The Methyltetrahydro-ß-Carbolines in Maca (Lepidium meyenii),” Evidence-Based Complementary and Alternative Medicine 6, no. 3 (September 2009): 315–16.
15 Israel and Laborde, 144.
16 S. M. Beck, H. Ruge, et al., “Effects of Ginkgo Biloba Extract EGb 761 on Cognitive Control Functions, Mental Activity of the Prefrontal Cortex and Stress Reactivity in Elderly Adults with Subjective Memory Impairment—a Randomized Double-Blind Placebo-Controlled Trial,” Human Psychopharmacology 31, no. 3 (May 2016): 227-42. doi: 10.1002/hup.2534.
17 K. Y. Yeh, Y. Z. Liu, and M. Y. Tai, “Ginkgo Extract Treatment Increases Noncontact Erections and Central Dopamine Levels in Rats: Role of the Bed Nucleus of the Stria Terminalis and the Medial Preoptic Area,” Psychopharmacology (Berl) 210, no. 4 (July 2010): 585-90. doi: 10.1007/s00213-010-1861-4. Epub 2010 Apr 23.
18 G. Cavallini, S. Caracciolo, and G. Vitali, “Carnitine versus Androgen Administration in the Treatment of Sexual Dysfunction, Depressed Mood, and Fatigue Associated with Male Aging,” Urology 63, no. 4 (April 2004): 641-46.
19 V. Gentile and P. Vicini, “Preliminary Observations on the Use of Propionyl-L-Carnitine in Combination with Sildenafil in Patients with Erectile Dysfunction and Diabetes,” Current Medical Research and Opinion 20, no. 9 (2004): 1377–84.
20 Israel and Laborde, 144.
21 J. Chen, Y. Wollman, T. Chernichovsky, A. Iaina, M. Sofer, and H. Matzkin, “Effect of Oral Administration of High Dose Nitric Oxide Donor L-Arginine in Men with Organic Erectile Dysfunction: Results of a Double-Blind, Randomized, Placebo-Controlled Study,” BJU International 83 (1999): 269–73.
22 Israel and Laborde, 144.
23 L. Cormio, “Oral L-Citrulline Supplementation Improves Erection Hardness in Men with Mild Erectile Dysfunction,” Urology 77 (2011): 119–22.
24 Takashi Suzuki and Masahiko Morita, “The Effects on Plasma L-Arginine Levels of Combined Oral L-Citrulline and L-Arginine Supplementation in Healthy Males,” Bioscience, Biotechnology, and Biochemistry 81, no. 2 (2017): 372–75.
25 Monica G. Ferrini, Su M. Hlaing, A. Chan, and J. N. Artaza, “Treatment with a Combination of Ginger, L-Citrulline, Muira Puama and Paullinia cupana Can Reverse the Progression of Corporal Smooth Muscle Loss, Fibrosis and Veno-occlusive Dysfunction in the Aging Rat,” Andrology 4, no. 1 (June 2015). Epub 2015 May 25. 26 http://www.newhope.com/supply-news-amp-analysis/toxicology-testing-catuama-brazilian-herbal-energy-product-healthy-adults.
27 P. Rohdewald, “A Review of the French Maritime Pine Bark Extract (Pycnogenol), a Herbal Medication with a Diverse Clinical Pharmacology,” International Journal of Clinical Pharmacology and Therapeutics 40 (2002): 158–68.
28 R. Stanislavov, V. Nikolova, and P. Rhodewald, “Improvement of Erectile Function with Prelox: A Randomized, Double-Blind, Placebo Controlled, Cross-Over Trial,” International Journal of Impotence Research 20 (2008): 173–80; A. Hiromitsu et al., “Clinical Assessment of a Supplement of Pycnogenol and L-arginine in Japanese Patients with Mild to Moderate Erectile Dysfunction,” Phytotherapy Research 26 (2012): 204–7.
29 D. F. Fitzpatrick, B. Bing, and P. Rohdewald, “Endotheliumdependent Vascular Effects of Pycnogenol,” Journal of Cardiovascular Pharmacology 32 (1998): 509–15.
30 B. Zhang et al., “A Review of Polyphenolics in Oak Woods,” International Journal of Molecular Sciences 16, no. 4 (April 2015): 6978–7014.
31 D. A. Shoskes and J. C. Nickel, “Quercetin for Chronic Prostatitis/Chronic Pelvic Pain Syndromes,” Urologic Clinics of North America 38 (2011): 279–84.
32 T. C. Lines and M. Ono, “FRS 1000, an Extract of Red Onion Peel, Strongly Inhibits Phosphodiesterase 5A (PDE 5A),” Phytomedicine 13, no. 4 (March 2006): 236–9. E-pub September 15, 2005.
33 https://www.google.com/patents/WO2011161655A1?cl=en
34 R. Estrada-Reyes, O. A. Ferreyra-Cruz, et al., “Prosexual Effect of Chrysactinia mexicana A. Gray (Asteraceae), False Damiana, in a Model of Male Sexual Behavior,” BioMed Research International (2016):2987917. Epub 2016 Aug 30.
35 M. Sutyarso, Kanedi, and E. Rosa, “Effects of Black Pepper (Piper nigrum Linn.) Extract on Sexual Drive in Male Mice,” Research Journal of Medicinal Plants 9 (2015): 42–47.
36 G. R. Shah, M. V. Chaudhari, et al., “Evaluation of a Multi-Herb Supplement for Erectile Dysfunction: A Randomized Double-Blind, Placebo Controlled Study,” BMC Complementary and Alternative Medicine 12 (September 15, 2012): 155. doi: 10.1186/1472-6882-12-155.
37 Jason R. Kovac, Michael Pan, Shawn Arent, and Larry I. Lipshultz, “Dietary Adjuncts for Improving Testosterone Levels in Hypogonadal Males,” American Journal of Men’s Health 10, no. 6 (November 2016).
38 M. K. Aghamir, R. Hosseini, and F. Alizadeh, “A Vacuum Device for Penile Elongation: Fact or Fiction?” BJU International 97, no. 4 (April 2006): 777–78.
39 M. R. Nowroozi, E. Amini, et al, “Applying Extender Devices in Patients with Penile Dysmorphophobia: Assessment of Tolerability, Efficacy, and Impact on Erectile Dysfunction,” Journal of Sexual Medicine 12 (2015): 1242–47.
40 http://www.bestmaleenhancement.me/exercises/increasing-size-with-male-enhancement-exercises.html.
41 H. Ghanem, S. Glina, P. Assalian, and J. Buvat, “Position Paper: Management of Men Complaining of a Small Penis Despite an Actually Normal Size,” Journal of Sexual Medicine 10 (2013): 294–303.
42 Paul Perito; Gabrielle Antonini: “Introduction of a Novel Office Based Non-Surgical Procedure Using Hyaluronic Acid Fillers for Aesthetic Penile Enhancement” IV World Congress of Medical Sexology Meeting, Miami 2015 (https://peritourology.com/penile-girth-enhancement-girthmax/).
43 R. Shamloul, “Treatment of Men Complaining of Short Penis,” Urology 65 (2005): 1183–85.
44 J. Lever, D. A. Frederick, and L. A. Peplau, “Does Size Matter? Men’s and Women’s Views on Penis Size across the Lifespan,” Psychology of Men and Masculinity 7 (2006): 129–43.
45 Raven Rowanchilde, “Male Genital Modification: A Sexual Selection Interpretation,” Human Nature 7, no. 2 (1996).
46 https://dicture.com/pages/about.
47 L. B. Mayers, D. A. Judelson, B. W. Moriarty, et al, “Prevalence of Bodyart (Body Piercing and Tattooing) in University Undergraduates and Incidence of Medical Complications,” Mayo Clinic Proceedings 77 (2002): 29–34.
48 V. S. Millner, B. H. Eichold, T. H. Sharpe, et al., “First Glimpse of the Functional Benefits of Clitoral Hood Piercings,” American Journal of Obstetrics and Gynecology 193 (2005): 675–76.
49 Rachel S. Edlin, David S. Aaronson, et al., “Squamous Cell Carcinoma at the Site of a Prince Albert’s Piercing,” Journal of Sexual Medicine 7, no. 6 (June 2010): 2280–3.
50 M. F. Ng, J. H. Clarkson, and F. J. Hogg, “Basal Cell Carcinoma Arising from Nasal Piercing: Cause or Coincidence,” Journal of Plastic, Reconstructive, and Aesthetic Surgery 63 (2010): e153–54.
51 Thomas Nelius and Myrna L. Armstrong, “Piercings: Diagnostic and Therapeutic Implications for Urologists,” Urology 78, no. 5 (2011).
CHAPTER 6 SEX, LIES, AND VIDEOTAPE: THE HARD FACTS ABOUT PORNOGRAPHY
1 S. A. Miller and E. S. Byers, “Actual and Desired Duration of Foreplay and Intercourse: Discordance and Misperceptions within Heterosexual Couples,” Journal of Sex Research 41 (2004): 301–9.
2 Benjamin Scuglia, (2004) “Sex Pigs,” Journal of Homosexuality 47, nos. 3–4 (2004): 185–88.
3 J. Griffith, M. Hayworth, et al., “A Comparison of Sexual Behaviors and Attitudes, Self-Esteem, Quality of Life, and Drug Use among Pornography Actors and a Matched Sample,” International Journal of Sexual Health 24 (2012): 254–66.
4 J. Griffith, M. Hayworth, et al., “Characteristics of Pornography Film Actors: Self-Report versus Perceptions of College Students,” Archives of Sexual Behavior 42 (2013): 637–47.
5 E. O. Laumann, J. H. Gagnon, R. T. Michael, and S. Michaels, The Social Organization of Sexuality: Sexual Practices in the United States (Chicago: University of Chicago Press, 1994).
6 S. Mitchell, “How to Put Condoms in the Picture,” New York Times, May 2, 2004. Retrieved from http://www.nytimes.com/2004/05/02/opinion/how-to-put-condomsin-thepicture.html.
7 C. J. Bishop, (2015). “‘Cocked, Locked and Ready to Fuck?’: A Synthesis and Review of the Gay Male Pornography Literature,” Psychology and Sexuality 6, no. 1 (2015): 5–27.
8 J. Kinser, “Michael Lucas Explains His Controversial Decision to Make Condom-Free Adult Films” (2014). Retrieved June 8, 2014 from http://www.queerty.com/michael-lucas-explains-his-controversialdecision-to-make-condom-free-adult-films-20140331.
9 R. Cathcart, “California: Suit on Regulation in Pornography Industry,” New York Times, July 18, 2009, 12.
10 Jeffrey Escoffier, “Porn Star/Stripper/Escort: Economic and Sexual Dynamics in a Sex Work Career,” Journal of Homosexuality 53, nos. 1-2 (2007): 173–200.
11 Griffith and Hayworth, “Characteristics of Pornography Film Actors.” 12 http://www.businessinsider.com/how-porn-drives-innovation-in-tech-2013-7.
13 http://www.nbcnews.com/business/business-news/things-are-looking-americas-porn-industry-n289431.
14 http://indianexpress.com/article/technology/tech-news-technology/each-adult-smartphone-user-will-watch-348-porn-videos-this-year-juniper-research/juniper research.
15 Personal conversation with Stephanie Buehler, PsyD.
16 Stephen Cranney, “Internet Pornography Use and Sexual Body Image in a Dutch Sample,” International Journal of Sexual Health 27, no. 3 (2015): 316–23.
17 N. Mondaini and R. Ponchiette, “Penile Length Is Normal in Most Men Seeking Penile Lengthening Procedures,” International Journal of Impotence Research 170, no. 3 (2002): 1057–58.
18 R. Shamloul, “Treatment of Men Complaining of Short Penis,” Urology 65, no. 6 (2005): 1183–85. PubMed: 15922413.
19 H. Ghanem, R. Shamloul, F. Khodeir, H. ElShafie, A. Kaddah, and I. Ismail, “Structured Management and Counseling for Patients with a Complaint of a Small Penis,” Journal of Sexual Medicine 4, no. 5 (2007): 1322–27. PubMed: 17419818.
20 B. Park, G. Wildon, et al., “Is Internet Pornography Causing Sexual Dysfunctions? A Review with Clinical Reports,” Behavioral Sciences 6, no. 3 (August 5, 2016). doi: 10.3390/bs6030017.
21 P. Capogrosso, M. Colicchia, E. Ventimiglia, G. Castagna, M. C. Clementi, N. Suardi, F. Castiglione, A. Briganti, F. Cantiello, R. Damiano, et al., “One Patient Out of Four with Newly Diagnosed Erectile Dysfunction Is a Young Man—Worrisome Picture from the Everyday Clinical Practice,” Journal of Sexual Medicine 10 (2013): 1833–41.
22 C. Sun, A. Bridges, J. Johnason, and M. Ezzell, “Pornography and the Male Sexual Script: An Analysis of Consumption and Sexual Relations,” Archives of Sexual Behavior 45 (2014): 1–12.
23 V. Voon, T. B. Mole, P. Banca, L. Porter, L. Morris, S. Mitchell, T. R. Lapa, J. Karr, N. A. Harrison, M. N. Potenza et al., “Neural Correlates of Sexual Cue Reactivity in Individuals with and without Compulsive Sexual Behaviours,” PLoS ONE 9 (2014): e102419.
24 M. D. Griffiths, “Compulsive Sexual Behaviour as a Behavioural Addiction: The Impact of the Internet and Other Issues,” Addiction 111 (2016): 2107–9.
25 P. Banca, L. S. Morris, S. Mitchell, N. A. Harrison, M. N. Potenza, and V. Voon, “Novelty, Conditioning and Attentional Bias to Sexual Rewards,” Journal of Psychiatric Research 72 (2016): 91–101.
26 A. Wéry and J. Billieux, “Online Sexual Activities: An Exploratory Study of Problematic and Non-Problematic Usage Patterns in a Sample of Men,” Computers in Human Behavior 56 (2016): 257–66.
27 Park and Wildon, “Is Internet Pornography Causing Sexual Dysfunctions?”
28 Samuel L. Perry, “Does Viewing Pornography Reduce Marital Quality Over Time? Evidence from Longitudinal Data,” Archives of Sexual Behavior. doi: 10.1007/s10508-016-0770-y.
29 Wéry and Billieux, “Online Sexual Activities.”
30 Park and Wildon, “Is Internet Pornography Causing Sexual Dysfunctions?”
31 K. S. Frohmader, J. Wiskerke, R. A. Wise, M. N. Lehman, and L. M. Coolen, “Methamphetamine Acts on Subpopulations of Neurons Regulating Sexual Behavior in Male Rats,” Neuroscience 166 (2010): 771–84.
32 K. K. Pitchers, V. Vialou, E. J. Nestler, S. R. Laviolette, M. N. Lehman, and L. M. Coolen, “Natural and Drug Rewards Act on Common Neural Plasticity Mechanisms with DFosB as a Key Mediator,” Journal of Neuroscience 33 (2013): 3434–42.
33 H. Garavan, J. Pankiewicz, A. Bloom, J. K. Cho, L. Sperry, T. J. Ross, B. J. Salmeron, R. Risinger, D. Kelley, and E. A. Stein, “Cue-Induced Cocaine Craving: Neuroanatomical Specificity for Drug Users and Drug Stimuli,” American Journal of Psychiatry 157 (2000): 1789–98.
34 Park and Wildon, “Is Internet Pornography Causing Sexual Dysfunctions?”
35 Voon et al., “Neural Correlates of Sexual Cue Reactivity in Individuals with and without Compulsive Sexual Behaviours.”
36 R. Z. Goldstein and N. D. Volkow, “Dysfunction of the Prefrontal Cortex in Addiction: Neuroimaging Findings and Clinical Implications,” Nature Reviews Neuroscience 12 (2011): 652–69.
37 D. Zillmann and J. Bryant, “Pornography’s Impact on Sexual Satisfaction,” Journal of Applied Social Psychology 18 (1988): 438–53.
38 T. Klucken, S. Wehrum-Osinsky, J. Schweckendiek, O. Kruse, and R. Stark, “Altered Appetitive Conditioning and Neural Connectivity in Subjects with Compulsive Sexual Behavior,” Journal of Sexual Medicine 13 (2016): 627–36.
39 L. Karila and A. Wery, “Sexual Addiction or Hypersexual Disorder: Different Terms for the Same Problem? A Review of the Literature,” Current Pharmaceutical Design 20, no. 25 (2014): 4012–20.
40 Park and Wildon, “Is Internet Pornography Causing Sexual Dysfunctions?”
41 Ibid.
42 B. A. Arnow et al., “Brain Activation and Sexual Arousal in Healthy, Heterosexual Males,” Brain 125 (2002): 1014–23.
43 B. Traeen and K. Daneback, “The Use of Pornography and Sexual Behaviour among Norwegian Men and Women of Differing Sexual Orientation,” Sexologies 22 (2013): e41–e48.
44 Cranney, “Internet Pornography Use and Sexual Body Image in a Dutch Sample.”
45 Ogi Ogas and Sai Gaddam, A Billion Wicked Thoughts: What the Internet Tells Us about Sexual Relationships (New York: Penguin, 2011).
CHAPTER 7 SHORTCUTS: ALL ABOUT CIRCUMCISION
1 W. D. Dunsmuir and E. M. Gordon, “The History of Circumcision,” BJU International 83, suppl. 1 (January 1, 1999): 1–12.
2 W. K. C. Morgan, “The Rape of the Phallus,” JAMA 193 (1965): 123–24. http://emedicine.medscape.com/article/1015820-overview#a4.
3 Terence H. Hull and Meiwita Budiharsana, “Male Circumcision and Penis Enhancement in Southeast Asia: Matters of Pain and Pleasure,” Reproductive Health Matters 9, no. 18 (November 2001).
4 Ibid.
5 Dunsmuir and Gordon, “The History of Circumcision.”
6 World Health Organization, UNAIDS, Neonatal and Child Male Circumcision: A Global Review, April 2010. ISBN 978-92-9-173855-7.
7 Hull and Budiharsana, “Male Circumcision and Penis Enhancement in Southeast Asia.”
8 B. J. Morris et al., “Circumcision Rates in the United States: Rising or Falling? What Effect Might the New Affirmative Pediatric Policy Statement Have?” Mayo Clinic Proceedings 89, no. 5 (May 2014): 677–86.
9 http://www.mayoclinicproceedings.org/article/S0025-6196(14)00036-6/abstract Source: Elsevier and www.mayoclinicproceedings.org/article/S0025-6196(14)00036-6/pdf.
10 S. S. Dave, A. M. Johnson, K. A. Fenton, C. H. Mercer, B. Erens, and K. Wellings, “Male Circumcision in Britain: Findings from a National Probability Sample Survey,” Sexually Transmitted Infections 79, no. 6 (2003): 499.
11 C. A. Angel et al., “Circumcision,” emedicine.Medscape.com, Dec. 6, 2016, http://emedicine.medscape.com/article/1015820-overview#a6.
12 Guy A. Bronselaer, Justine M. Schober, F. L. Heino, Meyer-Bahlburg, Guy T’Sjoen, Robert Vlietinck, and Piet B. Hoebeke, “Male Circumcision Decreases Penile Sensitivity as Measured in a Large Cohort,” BJUI 111, no. 5 (May 2013): 820–27.
13 J. A. Bossio et al., “Examining Penile Sensitivity in Neonatally Circumcised and Intact Men Using Quantitative Sensory Testing,” Journal of Urology 195, no. 6 (2016): 1848–53.
14 Kimberley Payne, Lea Thaler, Tuuli Kukkonen, Serge Carrier, and Yitzchak Binik, “Sensation and Sexual Arousal in Circumcised and Uncircumcised Men,” Journal of Sexual Medicine 4, no. 3 (May 2007): 667–74.
15 B. J. Morris et al., “Early Infant Male Circumcision: Systematic Review, Risk-Benefit Analysis, and Progress in Policy,” World Journal of Clinical Pediatrics 6, no. 1 (February 8, 2017): 89–102. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296634/#B22.
16 Ibid.
17 N. Fakjian et al., “An Argument for Circumcision. Prevention of Balanitis in the Adult,” Archives of Dermatology 126 (1990): 1046–47.
18 S. Edwards, “Balanitis and Balanoposthitis: A Review,” Genitourinary Medicine 72 (1996): 155–59.
19 T. Drake et al., “Phimosis in Childhood,” BMJ 346 (2013): f3678.
20 S. Celis et al., “Balanitis Xerotica Obliterans in Children and Adolescents: A Literature Review and Clinical Series,” Journal of Pediatric Urology 10 (2014): 34–39.
21 B. J. Morris and J. N. Krieger, “Penile Inflammatory Skin Disorders and the Preventive Role of Circumcision,” International Journal of Preventive Medicine (2017): in press.
22 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296634/#B22.
23 H. Thirumurthy, S. H. Masters, S. Rao, M. A. Bronson, M. Lanham, E. Omanga, et al., “Effect of Providing Conditional Economic Compensation on Uptake of Voluntary Medical Male Circumcision in Kenya: A Randomized Clinical Trial,” JAMA 312, no. 7 (2014): 703–11.
24 Morris et al., “Early Infant Male Circumcision.”
25 Ibid.
26 Ibid.
27 Ibid.
28 Ibid.
29 Ibid.
30 A. Abdulwahab-Ahmed et al., “Techniques of Male Circumcision,” Journal of Surgical Technique and Case Report 5, no. 1 (January-June 2013): 1–7.
31 https://books.google.com/books?isbn=0881255068.
32 Abdulwahab-Ahmed, “Techniques of Male Circumcision.”
33 Dunsmuir and Gordon, “The History of Circumcision.”
34 https://en.wikipedia.org/wiki/Foreskin_restoration#cite_note-ManHood-15.
CHAPTER 8 THE CULT OF PENISALITY: THE PENIS IN HISTORY, THE MEDIA, AND CYBERSPACE
1 M. Fahmy, Congenital Anomalies of the Penis (Switzerland: Springer International Publishing, 2017). doi: 10.1007/978-3-319-43310-3_3.
2 https://www.bustle.com/articles/115957-the-ideal-penis-in-history-by-each-obsessed-culture-nsfw.
4 https://www.youtube.com/watch?v=3Dt3IrdampY.
5 https://www.theguardian.com/film/2016/apr/05/female-nudity-three-times-likely-male-hollywood-films.
6 http://www.vulture.com/2016/05/game-of-thrones-penis-history.html.
7 https://www.washingtonpost.com/news/the-fix/wp/2017/05/19/a-moment-for-anthony-weiner/?utm_term=.e4a911b961ff.
8 http://www.cnn.com/ALLPOLITICS/1998/resources/lewinsky/timeline/.
9 http://www.menshealth.com/health/nba-champion-john-salley-prostate-exam.
10 https://www.theguardian.com/lifeandstyle/2017/may/27/me-and-my-penis-100-men-reveal-all.
11 https://dicture.com/pages/about.
13 http://www.puppetryofthepenis.com/.
14 https://play.google.com/store/apps/details?id=com.thedoctorsays.predicktor&hl=en.
15 https://healthcenter.uoregon.edu/Home/SexPositive.
18 https://www.gotinder.com/community-guidelines.
19 https://www.forbes.com/sites/janetwburns/2017/05/02/tinder-profiles-have-been-looted-again-this-time-for-teaching-ai-to-genderize-faces/#5454793d5454.
20 M. Boroughs, G. Cafri, and K. Thompson, “Male Body Depilation: Prevalence and Associated Features of Body Hair Removal,” Sex Roles 52 (2005): 637–44.
21 http://shop.ohmibod.com/Music-Vibrators.
24 http://www.alternet.org/sex-amp-relationships/internet-controlled-sex-machines-and-ipod-vibrators-sex-toy-industry-goes.
25 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491958/.
26 https://www.amazon.com/gp/product/B00PBSVW44/ref=as_at/?creativeASIN=B00PBSVW44&imprToken=o6AT3z3cq.aF6fSigHewQw&slotNum=3&ie=UTF8&th=1&linkCode=w61&tag=bustle2152-20&linkId=712bf1af318eaa7bf10e2f2b4a015d86.
27 https://www.forbes.com/sites/janetwburns/2016/07/15/adult-expo-founders-talk-15b-sex-toy-industry-after-20-years-in-the-fray/#5bb951925bb9.
CHAPTER 9 THE LOWDOWN: CAUSES OF ERECTILE DYSFUNCTION
1 M. G. Ferrini, S. M. Hlaing, A. Chan, and J. N. Artaza, “Treatment with a Combination of Ginger, L-Citrulline, Muira Puama and Paullinia cupana Can Reverse the Progression of Corporal Smooth Muscle Loss, Fibrosis and Veno-Occlusive Dysfunction in the Aging Rat,” Andrology 4, no. 1 (June 2015).
2 M. M. Wickremaratchi and J. G. Llewelyn, “Effects of Ageing on Touch,” Postgraduate Medical Journal 82, no. 967 (May 2006): 301–4.
3 C. V. Vlachopoulos et al., “Prediction of Cardiovascular Events and All-Cause Mortality with Erectile Dysfunction: A Systematic Review and Meta-Analysis of Cohort Studies,” Circulation: Cardiovascular Quality and Outcomes 6, no. 1 (2013): 99–109.
4 X. Cai, Y. Tian, T. Wu, C. X. Cao, S. Y. Bu, and K. J. Wang, “The Role of Statins in Erectile Dysfunction: A Systematic Review and Meta-Analysis,” Asian Journal of Andrology 16 (2014): 461–66.
5 Caldwell B. Esselstyn, Prevent and Reverse Heart Disease: The Revolutionary, Scientifically Proven, Nutrition-Based Cure (New York: Penguin, 2007).
6 S. S. Bassuk and J. E. Manson, “Epidemiological Evidence for the Role of Physical Activity in Reducing Risk of Type 2 Diabetes and Cardiovascular Disease,” Journal of Applied Physiology 99, no. 3 (2005): 1193–1204.
7 H. Wessells et al., “Effect of Intensive Glycemic Therapy on Erectile Function in Men with Type 1 Diabetes,” Journal of Urology 185, no. 5 (2011): 1828–34.
8 A. Cordero et al, “Erectile Dysfunction May Improve by Blood Pressure Control in Patients with High Risk Hypertension,” Postgraduate Medicine 122, no. 6 (2010): 51–56.
9 S. Lamina, C. G. Okoye, and T. T. Dagogo, “Therapeutic Effect of an Interval Exercise Training Program in the Management of Erectile Dysfunction in Hypertensive Patients,” Journal of Clinical Hypertension 11, no. 3 (2009) (Greenwich):125–29.
10 Christopher B. Harte and Cindy M. Meston, “Association between Smoking Cessation and Sexual Health in Men,” BJU International 109, no. 6 (March 2012): 888–96.
11 M. Pickett and M. Mittleman, “Secondhand Smoke and Erectile Dysfunction among Non-Smoking Men, NHANES 2001–2002,” Epidemiology 19, no. 6 (November 2008): S231.
12 Harte and Meston, “Association between Smoking Cessation and Sexual Health in Men.”
13 K. Esposito et al., “Effect of Lifestyle Changes on Erectile Dysfunction in Obese Men: A Randomized Controlled Trial,” JAMA 291, no. 24 (2004): 2978–84.
14 S. A. Martin, E. Atlantis, K. Lange, A. W. Taylor, P. O’Loughlin, G. A. Wittert, and members of the Florey Adelaide Male Ageing Study (FAMAS), “Predictors of Sexual Dysfunction Incidence and Remission in Men,” Journal of Sexual Medicine 11 (2014): 1136–47.
15 Stephanie Buehler, What Every Mental Health Professional Needs to Know About Sex, 2nd ed. (New York: Springer, 2017), 86.
16 Michelle Herberts and Kevin T. McVary, “Prescription Medications that Affect Sexual Function,” in T. S. Köhler and K. T. McVary (eds.), Contemporary Treatment of Erectile Dysfunction (Switzerland: Springer International, 2016), 154.
17 Buehler, What Every Mental Health Professional Needs to Know about Sex, 90–108.
CHAPTER 10 PENIS PILLS
1 http://www.medscape.com/viewarticle/542736_4.
2 P. Stroberg, A. Murphy, and T. Costigan, “Switching Patients with Erectile Dysfunction from Sildenafil Citrate to Tadalafil: Results of a European Multicenter, Open-Label Study of Patient Preference,” Clinical Therapeutics 25 (2003): 2724–37.
3 I. Eardley, V. Mirone, F. Montorsi et al., “An Open-Label, Multicentre, Randomized, Crossover Study Comparing Sildenafil Citrate and Tadalafil for Treating Erectile Dysfunction in Men Naïve to Phosphodiesterase 5 Inhibitor Therapy,” BJU International 96 (2005): 1323–32.
4 F. G. Kushner, M. Hand, S. C. Smith Jr., et al., “2009 Focused Updates: ACC/AHA Guidelines for the Management of Patients with ST-Elevation Myocardial Infarction (updating the 2004 guideline and 2007 focused update) and ACC/AHA/SCAI Guidelines on Percutaneous Coronary Intervention (updating the 2005 guideline and 2007 focused update): A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines,” Circulation 120 (2009): 2271–2306.
CHAPTER 11 NOW WHAT? WHEN PILLS DON’T WORK
1 C. G. McMahon, R. Samali, and H. Johnson, “Efficacy, Safety and Patient Acceptance of Sildenafil Citrate as Treatment for Erectile Dysfunction,” Journal of Urology 164, no. 4 (2000): 1192–96.
2 P. R. Sogari and C. Telöken, “Atropine Role in the Pharmacological Erection Test: Study of 228 Patients,” Journal of Urology 158, no. 5 (1997): 1760–63.
3 R. Shabsig et al., “Intracavernous Alprostadil Alfadex (EDEX/VIRIDAL) Is Effective and Safe in Patients with Erectile Dysfunction after Failing Sildenafil (Viagra),” Urology 55, no. 4 (2000): 477–80.
4 A. Nagai et al., “Intracavernous Injection of Prostaglandin E1 Is Effective in Patients with Erectile Dysfunction Not Responding to Phosphodiesterase 5 Inhibitors,” Acta Medica Okayama 59, no. 6 (2005): 279–80.
5 H. Derouet, M. Meeth, and H. Bewermeier, “Experience with a Papaverine/Phentolamine/Prostaglandin E1-Mixture in Non-Responders to Autoinjection Therapy,” Aktuelle Urol 27 (1996): 217–74.
6 Cynthia L. Bednarchik, Michael Kottwitz, and Scott W. Geiger, “Self-Injection, Transurethral, and Topical Therapy in Erectile Dysfunction,” in T. S. Köhler and K. T. McVary (eds.), Contemporary Treatment of Erectile Dysfunction (Switzerland: Springer International Publishing, 2016), 196.
7 A. K. Tsao and A. Nehra, “Intracavernosal Injection of Vasoactive Agents,” in J. J. Mulcahy (ed.), Current Clinical Urology: Male Sexual Function: A Guide to Clinical Management, 2nd ed. (Totowa, NJ: Humana Press, 2006).
8 Bednarchik, Kottwitz, and Geiger, “Self-Injection, Transurethral, and Topical Therapy in Erectile Dysfunction,” 198.
9 Sarah L. Hecht and Jason C. Hedges, “Vacuum Therapy for Erectile Dysfunction,” in T. S. Köhler and K. T. McVary (eds.), Contemporary Treatment of Erectile Dysfunction (Switzerland: Springer International Publishing, 2016), 175.
10 O. Lederer, Specification of Letter Patent. US patent No. 1,225,341. Accessed 8 May 1917.
11 D. Geddings S. Osbon, and G. D. Osbon, Erection Aid Device. US Patent Office. Accessed March 29, 1983.
12 Hecht and Hedges, “Vacuum Therapy for Erectile Dysfunction,” 178.
13 Yuan Jiuhong and Lin Haochen, “Molecular Mechanisms of Vacuum Therapy in Penile Rehabilitation: A Novel Animal Study,” European Urology 58 (2010): 773–80.
14 T. Sellers, M. Dineen, E. A. Salem, and S. K. Wilson, “Vacuum Preparation, Optimization of Cylinder Length and Postoperative Daily Inflation Reduces Complaints of Shortened Penile Length Following Implantation of Inflatable Penile Prosthesis,” Advances in Sexual Medicine 3, no. 1 (2013): 14–18.
15 M. K. Aghamir, R. Hosseini, and F. Alizadeh, “A Vacuum Device for Penile Elongation: Fact or Fiction?” BJU International 97, no. 4 (2006): 777–78.
16 Hecht and Hedges, “Vacuum Therapy for Erectile Dysfunction,” 180.
17 Bednarchik, Kottwitz, and Geiger, “Self-Injection, Transurethral, and Topical Therapy in Erectile Dysfunction,” 202.
18 R. Raina et al., “Combination Therapy: Medicated Urethral System for Erection Enhances Sexual Satisfaction in Sildenafil Citrate Failure Following Nerve-Sparing Radical Prostatectomy,” Journal of Andrology 26, no. 6 (2005): 757–60.
19 T. S. Köhler, R. Pedro, K. Hendlin, W. Utz, R. Ugarte, P. Reddy et al., “A Pilot Study on the Early Use of the Vacuum Erection Device after Radical Retropubic Prostatectomy,” BJU International 100, no. 4 (2007): 858–62.
CHAPTER 12 PUMP IT UP! SURGICAL IMPLANTS FOR ERECTILE DYSFUNCTION
1 Hernan Carrion and Daniel Martinez, “A History of the Penile Implant to 1974,” Sexual Medicine Reviews 4, no. 3 (July 2016): 285–93.
2 Gerard D. Henry, “Historical Review of Penile Prosthesis Design and Surgical Techniques: Part 1 of a Three-Part Review Series on Penile Prosthetic Surgery,” Journal of Sexual Medicine 6 (2009): 675–81.
3 T. Sellers, M. Dineen, E. A. Salem, and S. K. Wilson, “Vacuum Preparation, Optimization of Cylinder Length and Postoperative Daily Inflation Reduces Complaints of Shortened Penile Length Following Implantation of Inflatable Penile Prosthesis,” Advances in Sexual Medicine 3, no. 1 (2013): 14–18.
4 S. K. Wilson, J. R. Delk, E. A. Salem, and M. A. Cleves, “Long Term Survival of Inflatable Penile Prostheses: Single Surgical Group Experience with 2,384 First Time Implants Spanning Two Decades,” Journal of Sexual Medicine 4 (2007): 1074–79.
5 Kenneth J. DeLay Jr. and Tobias S. Köhler, “Penile Prosthesis,” in T. S. Köhler and K. T. McVary (eds.), Contemporary Treatment of Erectile Dysfunction (Switzerland: Springer International Publishing, 2016), 218.
6 Ibid.
7 Ibid., 214.
8 J. W. Moul and D. G. McLeod, “Negative Pressure Devices in the Explanted Penile
Prosthesis Population,” Journal of Urology 142, no. 3 (1989): 729–31.
CHAPTER 13 RUNNING ON EMPTY: LOW TESTOSTERONE
1 F. Giuliano, O. Rampin, A. Schirar, A. Jardin, and J. P. Rousseau, “Autonomic Cntrol of Penile Ereion: Modulation by Testosterone in the Rat,” Journal of Neuroendocrinology 5 (1993): 677–83.
2 R. S. Rogers, T. M. Graziottin, C. S. Lin, Y. W. Kan, and T. F. Lue, “Intracavernosal Vascular Endothelial Growth Factor (VEGF) Injection and Adeno-Associated Virus-Mediated VEGF Gene Therapy Prevent and Reverse Venogenic Erectile Dysfunction in Rats,” International Journal of Impotence Research 15 (2003): 26–37.
3 A. M. Traish, P. Toselli, S. J. Jeong, and N. N. Kim, “Adipocyte Accumulation in Penile Corpus Cavernosum of the Orchiectomized Rabbit: A Potential Mechanism for Veno-Occlusive Dysfunction in Androgen Deficiency,” Journal of Andrology 26 (2005): 242–48.
4 J. Anaissie, N. H. Roberts, P. Wang, and F. A. Yafi, “Testosterone Replacement Therapy and Components of the Metabolic Syndrome,” Sexual Medicine Reviews (April 2017), no. 2: 200–210.
5 Ibid.
6 J. E. Morley, E. Charlton, P. Patrick, et al., “Validation of a Screening Questionnaire for Androgen Deficiency in Aging Males,” Metabolism 49 (2000): 1239–42.
7 Mark S. Hockenberry and Puneet Masson, “Hormonal Evaluation and Therapy of Erectile Dysfunction,” in K. T. Köhler and K. T. McVary (eds.), Contemporary Treatment of Erectile Dysfunction (Switzerland: Springer International Publishing, 2016), 196.
8 Thomas G. Travison Andre B. Araujo, Varant Kupelian, Amy B. O’Donnell, and John B. McKinlay, “The Relative Contributions of Aging, Health, and Lifestyle Factors to Serum Testosterone Decline in Men,” Journal of Clinical Endocrinology and Metabolism 92, no. 2 (2007): 549–55.
9 T. Mulligan, M. F. Frick, Q. C. Zuraw, et al., “Prevalence of Hypogonadism in Males Aged at Least 45 Years: The HIM Study,” International Journal of Clinical Practice 60 (2006): 762–69.
10 Ibid.
11 R. Merai, C. Siegel, M. Rakotz, P. Basch, J. Wright, B. Wong, and P. Thorpe, “CDC Grand Rounds: A Public Health Approach to Detect and Control Hypertension,” Morbidity and Mortality Weekly Report 65, no. 45 (November 18, 2016): 1261–64.
12 D. Mozaffarian, E. J. Benjamin, A. S. Go, D. K. Arnett, M. J. Blaha, M. Cushman, et al., “Heart Disease and Stroke Statistics—2015 Update: A Report from the American Heart Association,” Circulation (December 17, 2014). Epub ahead of print.
13 Anaissie et al., “Testosterone Replacement Therapy and Components of the Metabolic Syndrome.”
14 Paul C. Henring, Bong-Sup Park, and Jeong-Su Kim, “Physiological Decrements during Sustained Military Operational Stress,” Military Medicine 176, no. 9 (2011): 991.
15 A. S. Dobs, M. A. Dempsey, P. W. Ladenson, et al., “Endocrine Disorders in Men Infected with Human Immunodeficiency Virus,” American Journal of Medicine 84, no. 3, pt 2 (March 1988): 611–16.
16 A. C. Hackney, “Effects of Endurance Exercise on the Reproductive System of Men: The Exercise-Hypogonadal Male Condition,” Journal of Endocrinological Investigation 31 (2008): 932–38.
17 Stephen E. Borst and Thomas Mulligan, “Testosterone Replacement Therapy for Older Men,” Clinical Interventions in Aging 2, no. 4 (December 2007): 561–66. Published online December 2007. PMCID: PMC2686341.
18 http://natesto.com/pdf/Natesto_Prescribing_Information_Consumers.pdf.
19 T. C. Hsieh, A. W. Pastuszak, K. Hwang, and L. I. Lipshultz, “Concomitant Intramuscular Human Chorionic Gonadotropin Preserves Spermatogenesis in Men Undergoing Testosterone Replacement Therapy,” Journal of Urology 189 (2013): 647–50.
20 A. M. Traish, A. T. Guay, and A. Morgentaler, “Death by Testosterone? We Think Not!” Journal of Sexual Medicine 11 (2014): 624-29.
21 T. C. Cheetham, J. An, S. J. Jacobsen, F. Niu, S. Sidney, C. P. Quesenberry, and S. K. VanDenEeden, “Association of Testosterone Replacement with Cardiovascular Outcomes Among Men With Androgen Deficiency,” JAMA Internal Medicine 177, no. 4 (April 1, 2017): 491–99. doi: 10.1001/jamainternmed.2016.9546.
22 M. M. Shores, N. L. Smith, C. W. Forsberg, B. D. Anawalt, and A. M. Matsumoto, “Testosterone Treatment and Mortality in Men with Low Testosterone,” Journal of Clinical Endocrinology and Metabolism 97, no. 6 (2012): 2050–58.
CHAPTER 14 PUT IT IN YOUR MOUTH: HOW GRUB AFFECTS YOUR NUB
1 A. C. Torregrossa, M. Aranke, and N. S. Bryan, “Nitric Oxide and Geriatrics: Implications in Diagnostics and Treatment of the Elderly,” Journal of Geriatric Cardiology 8, no. 4 (December 2011): 230–42.
2 P. Santamaria, “Nitrate in Vegetables: Toxicity, Content, Intake and EC Regulation,” Journal of the Science of Food and Agriculture 86 (2006): 10–17.
3 J. O. Lundberg, E. Weitzberg, and M. T. Gladwin, “The Nitrate-Nitrite-Nitric Oxide Pathway in Physiology and Therapeutics,” Nature Reviews Drug Discovery 7, no. 2 (February 2008): 156–67. doi: 10.1038/nrd2466.
6 K. Esposito, F. Giugliano, M. De Sio, D. Carleo, C. Di Palo, M. D’Armiento, and D. Giugliano, “Dietary Factors in Erectile Dysfunction,” International Journal of Impotence Research 18 (2006): 370–74.
7 P. N. Singh, J. Sabaté, and G. E. Fraser, “Does Low Meat Consumption Increase Life Expectancy in Humans?” American Journal of Clinical Nutrition 78, 3 suppl. (September 2003): 526S-32S.
8 D. L. J. Freed, “Do Dietary Lectins Cause Disease? The Evidence Is Suggestive—and Raises Interesting Possibilities for Treatment,” BMJ 318, no. 7190 (April 1999): 1023–24; Steven R. Gundry, MD, The Plant Paradox: The Hidden Dangers in “Healthy” Foods That Cause Disease and Weight Gain (New York: Harper Collins, 2017).
9 B. Liu, H. J Bian, and J. K. Bao, “Plant Lectins: Potential Antineoplastic Drugs from Bench to Clinic,” Cancer Letters 287 (2010): 1–12; A. Pusztai, S. Bardocz, and M. A. Martin-Cabrejas, “The Mode of Actions of ANFs on the Gastrointestinal Tract and Its Microflora,” Fourth International Workshop on Antinutrional Factors in Legume Seeds and Oilseeds vol. 110 (2004): 87–100.
10 Adriana Buitrago-Lopez and Jean Sanderson, “Chocolate Consumption and Cardiometabolic Disorders: Systematic Review and Meta-Analysis,” BMJ (2011): 343.
11 M. Aldemir et al., “Pistachio Diet Improves Erectile Function Parameters and Serum Lipid Profiles in Patients with Erectile Dysfunction,” International Journal of Impotence Research 23, no. 1 (January–February 2011):32–8. doi: 10.1038/ijir.2010.33.
12 Katherine Esposito and Dario Giugliano, “Diet and Inflammation: A Link to Metabolic and Cardiovascular Diseases,” European Heart Journal 27 (2006): 15–20.
13 P. K. Nguyen, S. Lin, and P. Heidenreich, “A Systematic Comparison of Sugar Content in Low-Fat vs Regular Versions of Food,” Nutrition and Diabetes 6, no. 1 (January 25, 2016): e193. doi: 10.1038/nutd.2015.43.P.
14 Cristin E. Kearns, Laura A. Schmidt, and Stanton A. Glantz, “Sugar Industry and Coronary Heart Disease Research: A Historical Analysis of Internal Industry Documents,” JAMA Internal Medicine 176, no. 11 (2016): 1680–85.
15 Christian F. Rueda-Clausen and Federico A. Silva, “Olive, Soybean and Palm Oils Intake Have a Similar Acute Detrimental Effect over the Endothelial Function in Healthy Young Subjects,” Nutrition, Metabolism & Cardiovascular Diseases 17 (2007): 50–57.
16 Esposito et al., “Dietary Factors in Erectile Dysfunction.”
17 Esposito and Giugliano, “Diet and Inflammation: A Link to Metabolic and Cardiovascular Diseases.”
18 “Position of the American Dietetic Association: Vegetarian Diets,” Journal of the American Dietetic Association 109 (2009): 1266–82.
19 C. B. Esselstyn Jr., Prevent and Reverse Heart Disease (New York: Penguin Group, 2007).
20 D. Ornish, G. Weidner, W. R. Fair, et al., “Intensive Lifestyle Changes May Affect the Progression of Prostate Cancer,” Journal of Urology 174 (2005): 1065–70.
21 D. K. Oliver, Maddocks, Dimitris Athineos, Eric C. Cheung, Pearl Lee, Tong Zhang, Niels J. F. van den Broek, Gillian M. Mackay, Christiaan F. Labuschagne, David Gay, Flore Kruiswijk, Julianna Blagih, David F. Vincent, Kirsteen J. Campbell, Fatih Ceteci, Owen J. Sansom, Karen Blyth, and Karen H. Vousden, “Modulating the Therapeutic Response of Tumours to Dietary Serine and Glycine Starvation,” Nature 544 (April 20, 2017).
22 T. C. Campbell, B. Parpia, and J. Chen, “Diet, Lifestyle, and the Etiology of Coronary Artery Disease: The Cornell China Study,” American Journal of Cardiology 82 (1998): 18T-21T.
23 Paul N. Appleby, Francesca L. Crowe, Kathryn E. Bradbury, Ruth C. Travis, and Timothy J. Key, “Mortality in Vegetarians and Comparable Nonvegetarians in the United Kingdom,” American Journal of Clinical Nutrition 103, no. 1 (January 2016): 218–30.
24 https://www.davita.com/kidney-disease/diet-and-nutrition/diet-basics/hidden-phosphorus-in-your-diet-and-how-to-control-it/e/5322.
25 Seung Ki Min, Kwibok Choi, Soon Ki Kim, Gyeong In Lee, and In-Chang Cho, “Phosphorus as Predictive Factor for Erectile Dysfunction in Middle Aged Men: A
Cross Sectional Study in Korea,” Investigative and Clinical Urology 57 (2016): 442–48.
26 K. Esposito, F. Nappo, F. Giugliano, G. Giugliano, R. Martella, and D. Giugliano, “Effect of Dietary Antioxidants on Postprandial Endothelial Dysfunction Induced by a High-Fat Meal in Healthy Subjects,” American Journal of Clinical Nutrition 77 (2003): 139–43.
CHAPTER 15 SEXERCISE: FLEX YOUR SEX
1 J. Szostak and P. Laurant, “The Forgotten Face of Regular Physical Exercise: A ‘Natural’ Anti-Atherogenic Activity,” Clinical Science (London) 121, no. 3 (2011): 91–106.
2 L. C. Agostini, J. M. Netto, M. V. Miranda, and A. A. Figueiredo, “Erectile Dysfunction Association with Physical Activity Level and Physical Fitness in Men Aged 40–75 Years,” International Journal of Impotence Research 23 (2011): 115–21.
3 B. P. Gupta, M. H. Murad, M. M. Clifton, L. Prokop, A. Nehra, and S. L. Kopecky, “The Effect of Lifestyle Modification and Cardiovascular Risk Factor Reduction on Erectile Dysfunction: A Systematic Review and Meta-analysis,” Archives of Internal Medicine 171, no. 20 (2011): 1797–1803.
4 D. Kalka, Z. Domagala, J. Dworak, et al., “Association between Physical Exercise and Quality of Erection in Men with Ischaemic Heart Disease and Erectile Dysfunction Subjected to Physical Training,” Kardiologia Polska 71 (2013): 573–80.
5 Abdulmaged M. Traish and James T. Trusslerin, “Effects of Lifestyle Changes and Testosterone Therapy on Erectile Function,” in T. S. Köhler and K. T. McVary (eds.), Contemporary Treatment of Erectile Dysfunction (Switzerland: Springer International Publishing, 2016), 109.
6 J. R. White, D. A. Case, D. McWhirter, and A. M. Mattison, “Enhanced Sexual Behavior in Exercising Men,” Archives of Sexual Behavior 19 (1990): 193–209.
7 R. R. Wing, R. C. Rosen, J. L. Fava, J. Bahnson, F. Brancati, I. N. Gendrano, A. Kitabchi, S. H. Schneider, and T. A. Wadden, “Effects of Weight Loss Intervention on Erectile Function in Older Men with Type 2 Diabetes in the Look AHEAD Trial,” Journal of Sexual Medicine 7, no. 1, Pt. 1 (2010): 156–65.
8 A. M. Traish, “Testosterone and Weight Loss: The Evidence,” Current Opinion in Endocrinology, Diabetes, and Obesity 21, no. 5 (2014): 313–22.
9 M. Sedliak, T. Finni, S. Cheng, W. J. Kraemer, and K. Häkkinen, “Effect of Time-of-Day-Specific Strength Training on Serum Hormone Concentrations and Isometric Strength in Men,” Chronobiology International 24, no. 6 (2007): 1159–77.
10 A. C. Hackney, “Effects of Endurance Exercise on the Reproductive System of Men: The ‘Exercise-Hypogonadal Male Condition,’” Journal of Endocrinological Investigation 31 (2008): 932–38.
11 Ilan Leibovitcha and Yoram Morb, “The Vicious Cycling: Bicycling Related Urogenital Disorders,” European Urology 47 (2005): 277–87.
12 F. Sommer, U. Schwarzer, T. Klotz, H. P. Caspers, G. Haupt, and U. Engelmann, “Erectile Dysfunction in Cyclists. Is There Any Difference in Penile Blood Flow during Cycling in an Upright versus a Reclining Position?” European Urology 39 (2001): 720–23.
13 Steven M. Schrader, Michael J. Breitenstein, John C. Clark, Brian D. Lowe, and Terry W. Turner, “Nocturnal Penile Tumescence and Rigidity Testing in Bicycling Patrol Officers,” Journal of Andrology 23, no. 6 (2002): 927–34. doi:10.1002/j.1939-4640.2002.tb02352.x.
14 F. Sommer, D. Konig, C. Graft, U. Schwarzer, C. Bertram, T. Klotz, et al., “Impotence and Genital Numbness in Cyclists,” International Journal of Sports Medicine 22 (2001): 410–13.
15 K. V. Andersen and G. Bovim, “Impotence and Nerve Entrapment in Long Distance Amateur Cyclists,” Acta Neurologica Scandinavica 95 (1997): 233–40.
16 M. Ueno, “The So-Called Coition Death,” Japanese Journal of Legal Medicine 17 (1963): 330–40.
17 http://www.medscape.com/viewarticle/450572.
18 Grace Dorey and Mark Speakman, “Randomised Controlled Trial of Pelvic Floor Muscle Exercises and Manometric Biofeedback for Erectile Dysfunction,” British Journal of General Practice 54 (2004): 819–25.
19 G. Piediferro, E. M. Colpi, F. Castiglioni, et al., “Premature Ejaculation. 3. Therapy,” Archives of Italian Urology and Andrology 76 (2004): 192–98.
20 Andrew L. Siegel, “Pelvic Floor Muscle Training in Males: Practical Applications,” Urology 84 (2014): 1e7.
CHAPTER 16 MY FIVE-STEP PLAN FOR MAXIMUM PENIS HEALTH
1 J. O. Lundberg, E. Weitzberg, and M. T. Gladwin, “The Nitrate-Nitrite-Nitric Oxide Pathway in Physiology and Therapeutics,” Nature Reviews Drug Discovery 7, no. 2 (February 2008): 156–67. doi: 10.1038/nrd2466.
2 G. B. Haber, K. W. Heaton, D. Murphy, and L. F. Burroughs, “Depletion and Disruption of Dietary Fibre. Effects on Satiety, Plasma-Glucose, and Serum-Insulin,” Lancet 2, no. 8040 (October 1977): 679–82.
3 C. B. Esselstyn Jr., Prevent and Reverse Heart Disease (New York: Penguin Group, 2007).
4 D. Ornish, G. Weidner, W. R. Fair, et al., “Intensive Lifestyle Changes May Affect the Progression of Prostate Cancer,” Journal of Urology 174 (2005): 1065–70.
5 http://www.benbellavegan.com/book/the-china-study-revised-and-expanded-edition/.
6 http://michaelpollan.com/books/in-defense-of-food/.
7 http://www.thugkitchen.com/https://minimalistbaker.com/.
8 Christian F. Rueda-Clausen and Federico A. Silva, “Soybean and Palm Oils Intake Have a Similar Acute Detrimental Effect over the Endothelial Function in Healthy Young Subjects,” Nutrition, Metabolism & Cardiovascular Diseases 17 (2007): 50–57.
9 K. Esposito, F. Nappo, F. Giugliano, G. Giugliano, R. Martella, and D. Giugliano, “Effect of Dietary Antioxidants on Postprandial Endothelial Dysfunction Induced by a High-Fat Meal in Healthy Subjects,” American Journal of Clinical Nutrition 77 (2003): 139–43.
10 Katherine Esposito and Dario Giugliano, “Diet and Inflammation: A Link to Metabolic and Cardiovascular Diseases,” European Heart Journal 27 (2006): 15–20.
11 Seung Ki Min, Kwibok Choi, Soon Ki Kim, Gyeong In Lee, and In-Chang Cho, “Phosphorus as Predictive Factor for Erectile Dysfunction in Middle-Aged Men: A
Cross Sectional Study in Korea,” Investigative and Clinical Urology 57 (2016): 442–48.
12 https://www.davita.com/kidney-disease/diet-and-nutrition/diet-basics/hidden-phosphorus-in-your-diet-and-how-to-control-it/e/5322.
13 Seung et al, “Phosphorus as Predictive Factor for Erectile Dysfunction in Middle Aged Men.”
14 Adriana Buitrago-Lopez and Jean Sanderson, “Chocolate Consumption and Cardiometabolic Disorders: Systematic Review and Meta-Analysis,” BMJ 343 (2011).
15 M. Serafini et al., “Plasma Antioxidants from Chocolate,” Nature 424, no. 1013
(August 28, 2003): doi: 10.1038/4241013a.
16 K. Esposito, F. Giugliano, M. De Sio, D. Carleo, C. Di Palo1, M. D’Armiento, and D. Giugliano1, “Dietary Factors in Erectile Dysfunction,” International Journal of Impotence Research 18 (2006): 370–74.
17 Esposito and Giugliano, “Diet and Inflammation: A Link to Metabolic and Cardiovascular Diseases.”
18 L. C. Agostini, J. M. Netto, M. V. Miranda, and A. A. Figueiredo, “Erectile Dysfunction Association with Physical Activity Level and Physical Fitness in Men Aged 40–75 Years,” International Journal of Impotence Research 23 (2011): 115–21.
19 J. Szostak and P. Laurant, “The Forgotten Face of Regular Physical Exercise: A ‘Natural’ Anti-Atherogenic Activity,” Clinical Science (London) 121, no. 3 (2011): 91–106.
20 J. Bahnson, F. Brancati, I. N. Gendrano A. Kitabchi, S. H. Schneider, and T. A. Wadden, “Effects of Weight Loss Intervention on Erectile Function in Older Men with Type 2 Diabetes in the Look AHEAD Trial,” Journal of Sexual Medicine 7, no. 1, pt. 1 (2010): 156–65.
21 A. M. Traish, “Testosterone and Weight Loss: The Evidence,” Current Opinion in Endocrinology, Diabetes & Obesity 21, no. 5 (2014): 313–22.
22 Szostak and Laurant, “The Forgotten Face of Regular Physical Exercise.”
23 J. R. White, D. A. Case, D. McWhirter, and A. M. Mattison, “Enhanced Sexual Behavior in Exercising Men,” Archives of Sexual Behavior 19 (1990): 193–209.
24 Agostini et al., “Erectile Dysfunction Association with Physical Activity Level and Physical Fitness in Men Aged 40–75 Years.”
25 F. Sommer, D. Konig, C. Graft, U. Schwarzer, C. Bertram, T. Klotz, et al., “Impotence and Genital Numbness in Cyclists,” International Journal of Sports Medicine 22 (2001): 410–13.
26 Grace Dorey and Mark Speakman, “Randomised Controlled Trial of Pelvic Floor Muscle Exercises and Manometric Biofeedback for Erectile Dysfunction,” British Journal of General Practice 54 (2004): 819–25.
27 Andrew L. Siegel, “Pelvic Floor Muscle Training in Males: Practical Applications,” Urology 84 (2014): 1e7.
28 https://www.juniperresearch.com/researchstore/content-applications/digital-adult-content/trends-forecasts-revenueopportunities?utm_source=juniperpr&utm_medium=email&utm_campaign=adult15pr1.
29 Park, Wildon, et al., “Is Internet Pornography Causing Sexual Dysfunctions? A Review with Clinical Reports,” Behavioral Sciences 6 (2016): 17. doi: 10.3390/bs6030017.
30 Ibid., ref. 86.
31 S. Kühn and J. Gallinat, “Brain Structure and Functional Connectivity Associated with Pornography Consumption: The Brain on Porn,” JAMA Psychiatry 71 (2014): 827–34.
32 B. A. Arnow, J. E. Desmond, L. L. Banner, G. H. Glover, A. Solomon, M. L. Polan, T. F. Lue, and S. W. Atlas, “Brain Activation and Sexual Arousal in Healthy, Heterosexual Males,” Brain 125 (2002): 1014–23.
33 Park, Wildon, et al, ref. 37.
34 C. Sun, A. Bridges, J. Johnason, and M. Ezzell, “Pornography and the Male Sexual Script: An Analysis of Consumption and Sexual Relations,” Archives of Sexual Behavior 45 (2014): 1–12.
35 I. Landripet and A. Štulhofer, “Is Pornography Use Associated with Sexual Difficulties and Dysfunctions among Younger Heterosexual Men?” Journal of Sexual Medicine 12 (2015): 1136–39.
36 L. F. O’Sullivan, L. A. Brotto, E. S. Byers, J. A. Majerovich, and J. A. Wuest, “Prevalence and Characteristics of Sexual Functioning among Sexually Experienced Middle to Late Adolescents,” Journal of Sexual Medicine 11 (2014): 630–41.
37 P. Damiano, B. Alessandro, and F. Carlo, “Adolescents and Web Porn: A New Era of Sexuality,” International Journal of Adolescent Medicine and Health 28 (2015): 169–73.
38 Jenny Minarcik and T. Chad, “The Effects of Sexually Explicit Material Use on Romantic Relationship Dynamics,” Journal of Behavioral Addictions. doi: 10.1556/2006.5.2016.078.
39 Samuel L. Perry, “Does Viewing Pornography Reduce Marital Quality Over Time? Evidence from Longitudinal Data,” Archives of Sexual Behavior. doi: 10.1007/s10508-016-0770-y.
40 Stephen Cranney, “Internet Pornography Use and Sexual Body Image in a Dutch Sample,” International Journal of Sexual Health 27, no. 3 (2015): 316–23.
41 N. Mondaini and R. Ponchiette, “Penile Length Is Normal in Most Men Seeking Penile Lengthening Procedures,” International Journal of Impotence Research 170, no. 3 (2002): 1057–58.
42 Park, Wildon, et al.
43 H. A. Feldman, I. Goldstein, D. G. Hatzichristou, R. J. Krane, and J. B. McKinlay, “Impotence and Its Medical and Psychosocial Correlates: Results of the Massachusetts Male Aging Study,” Journal of Urology 151, no. 1 (1994): 54–61.
44 V. Kupelian, C. L. Link, and J. B. McKinlay, “Association between Smoking, Passive Smoking, and Erectile Dysfunction: Results from the Boston Area Community Health (BACH) Survey,” European Urology 52, no. 2 (2007): 416–22.
45 C. B. Harte and C. M. Meston, “Association between Smoking Cessation and Sexual Health in Men,” BJU International 109, no. 6 (2012): 888–96.
46 https://betobaccofree.hhs.gov.
47 https://www.cancer.gov/about-cancer/causes-prevention/risk/tobacco/quit-smoking-pdq.
48 F. Aydinoglu, S. N. Yilmaz, B. Coskun, N. Daglioglu, and N. Ogulener, “Effects of Ethanol Treatment on the Neurogenic and Endothelium-Dependent Relaxation of Corpus Cavernosum Smooth Muscle in the Mouse,” Pharmacological Reports 60 (2008): 725–34.
49 A. J. Wein and K. N. Van Arsdalen, “Drug-Induced Male Sexual Dysfunction,” Urologic Clinics of North America 15 (1988): 23–31.
50 A. Aversa, F. Rossi, D. Francomano, et al, “Early Endothelial Dysfunction as a Marker of Vasculogenic Erectile Dysfunction in Young Habitual Cannabis Users,” International Journal of Impotence Research 20 (2008): 566–73.
51 R. Shamloul and A. J. Bella, “Impact of Cannabis Use on Male Sexual Health,” Journal of Sexual Medicine 8 (2011): 971–75.
52 Michelle Herberts and Kevin T. McVary, “Prescription Medications that Affect Sexual Function,” in T. S. Köhler and K. T. McVary (eds.), Contemporary Treatment of Erectile Dysfunction (Switzerland: Springer International Publishing, 2016), 157.
53 Pablo Vallejo-Medina and Juan Carlos Sierra, “Effect of Drug Use and Influence of Abstinence on Sexual Functioning in a Spanish Male Drug-Dependent Sample: A Multisite Study,” Journal of Sexual Medicine 10, no. 2 (2013): 333–41.
54 Herberts and McVary, “Prescription Medications that Affect Sexual Function,” 152.
55 Rachel Leproult and Eve Van Cauter, “Effect of 1 Week of Sleep Restriction on Testosterone Levels in Young Healthy Men,” JAMA 305, no. 21 (June 1, 2011): 2173–74.
56 Alexander W. Pastuszak, Young M. Moon, Jason Scovell, Justin Badal, Dolores J. Lamb, Richard E. Link, and Larry I. Lipshultz, “Dysfunction in Male Nonstandard Shift Workers,” Urology 102 (2017): 121–25.
57 D. A. Kalmbach, J. T. Arnedt, V. Pillai, and J. A. Ciesla, “The Impact of Sleep on Female Sexual Response and Behavior: A Pilot Study,” Journal of Sexual Medicine 12, no. 5 (May 2015): 1221–32. doi: 10.1111/jsm.12858.
58 http://www.aasmnet.org/articles.aspx?id=3940.
59 Patrick E. Teloken, Eric B. Smith, Chris Lodowsky, Thomas Freedom, and John P. Mulhall, “Defining Association between Sleep Apnea Syndrome and Erectile Dysfunction,” Urology 67 (2006): 1033–37.
60 P. Perimenis, K. Karkoulias, S. Markou, K. Gyftopoulos, A. Athanasopoulos, G. Barbalias, V. Kiriazopoulou, and K. Spiropoulos, “Erectile Dysfunction in Men with Obstructive Sleep Apnea Syndrome: A Randomized Study of the Efficacy of Sildenafil and Continuous Positive Airway Pressure,” International Journal of Impotence Research 16 (2004): 256–60.
61 F. Fanfulla, S. Malaguti, T. Montaga, et al., “Erectile Dysfunction in Men with Obstructive Sleep Apnea: An Early Sign of Nerve Involvement,” Sleep 23 (2000): 775–81.
62 P. Lavie, P. Herer, and V. Hoffstein, “Obstructive Sleep Apnea Syndrome as Risk Factor for Hypertension: Population Study,” BMJ 320 (2000): 479–82. http://www.webmd.com/sleep-disorders/sleep-apnea/sleep-apnea-conditions#1.
63 Perimenis et al., “Erectile Dysfunction in Men with Obstructive Sleep Apnea Syndrome.”
64 https://sleep.org/articles/catching-up-on-sleep/.
CHAPTER 17 GETTING BENT OUT OF SHAPE: PEYRONIE’S DISEASE
1 J. F. Smith, W. O. Brant, V. Fradet, A. W. Shindel, E. Vittinghoff, T. Chi, et al., “Penile Sonographic and Clinical Characteristics in Men with Peyronie’s Disease,” Journal of Sexual Medicine 6, no. 10 (2009): 2858–67.
2 Louis-Paul Fischer, Jean-Jacques Ferrandis, and Jean-Eric Blatteau, “François de la Peyronie, from Montpellier (1678–1747). ‘Surgery Restorer’ and Universal Spirit. The Soul, Music, Rooster Eggs,” Histoire des Sciences Medicales 43, no. 3 (2010): 241–48.
3 T. Lue, “The Anatomy of the Tunica Albuginea in the Normal Penis and Peyronie’s Disease,” Journal of Urology 157 (1997): 276–81.
4 R. Tal, M. Heck, P. Teloken, T. Siegrist, C. J. Nelson, and J. P. Mulhall, “Peyronie’s Disease Following Radical Prostatectomy: Incidence and Predictors,” Journal of Sexual Medicine 7, no. 3 (2010): 1254–61.
5 James R. Craig, William O. Brant, James F. Smith, and Tom F. Lue, “Peyronie’s Disease: Natural History, Diagnosis, and Medical Therapy,” in T. S. Köhler and K. T. McVary (eds.), Contemporary Treatment of Erectile Dysfunction (Switzerland: Springer International Publishing, 2016), 291.
6 M. R. Safarinejad, S. Y. Hosseini, and A. A. Kolahi, “Comparison of Vitamin E and Propionyl-l-Carnitine, Separately or in Combination, in Patients with Early Chronic Peyronie’s Disease: A Double-Blind, Placebo Controlled, Randomized Study,” Journal of Urology 178 (2007): 1398–1403.
7 G. Cavallini, G. Biagiotti, A. Koverech, and G. Vitali, “Oral Propionyl-l-Carnitine and Intraplaque Verapamil in the Therapy of Advanced and Resistant Peyronie’s Disease,” BJU International 89 (2002): 895–900.
8 C. C. Carson, “Potassium Para-Aminobenzoate for the Treatment of Peyronie’s Disease: Is It Effective?” Techniques in Urology 3, no. 3 (1997): 135–39.
9 Craig et al., “Peyronie’s Disease: Natural History, Diagnosis, and Medical Therapy,” 290.
10 P. Gontero, M. Di Marco, G. Giubilei, R. Bartoletti, G. Pappagallo, A. Tizzani, et al., “Use of Penile Extender Device in the Treatment of Penile Curvature as a Result of Peyronie’s Disease. Results of a Phase II Prospective Study,” Journal of Sexual Medicine 6, no. 2 (2009): 558–66.
11 Laurence A. Levine, Mark Newell, and Frederick L. Taylor, “Penile Traction Therapy for Treatment of Peyronie’s Disease: A Single-Center Pilot Study,” Journal of Sexual Medicine 5 (2008): 1468–73.
12 Eric Shaw, Faysal A. Yafi, Premsant Sangkum, and Wayne J. G. Hellstrom, “Injection Therapy for Peyronie’s Disease,” in T. S. Köhler and K. T. McVary (eds.), Contemporary Treatment of Erectile Dysfunction (New York: Springer, 2016), 302, 303.
13 Michael R. Abern, Stephen Larsen, and Laurence A. Levine, “Combination of Penile Traction, Intralesional Verapamil, and Oral Therapies for Peyronie’s Disease,” Journal of Sexual Medicine 9, no. 3 (March 2012): 288–95.
14 Shaw et al., “Injection Therapy for Peyronie’s Disease.”
15 F. A. Yafi, M. R. Pinsky, C. Stewart, P. Sangkum, E. Ates, L. W. Trost, et al., “The Effect of Duration of Penile Traction Therapy in Patients Undergoing Intralesional Injection Therapy for Peyronie’s Disease,” Journal of Urology 194, no. 3 (2015): 754–58.
16 Craig et al., “Peyronie’s Disease: Natural History, Diagnosis, and Medical Therapy,” 295.
17 J. M. Greenfield, S. J. Shah, and L. A. Levine, “Verapamil versus Saline in Electromotive Drug Administration for Peyronie’s Disease: A Double-Blind, Placebo Controlled Trial,” Journal of Urology 177, no. 8 (2007): 972–75.
18 D. J. Martin, K. Badwan, M. Parker, and J. P. Mulhall, “Transdermal Application of Verapamil Gel to the Penile Shaft Fails to Infiltrate the Tunica Albuginea,” Journal of Urology 168, no. 6 (2002): 2483–85.
19 J. A. Levy, M. Marchand, L. Iorio, G. Zribi, and M. P. Zahalsky, “Effects of Stem Cell Treatment in Human Patients with Peyronie Disease,” Journal of the American Osteopathic Association 115, no. 10 (October 2015): e8-13. doi: 10.7556/jaoa.2015.124.
20 A. B. Reed-Maldonado and T. F. Lue, “A Meta-analysis of Extracorporeal Shock Wave Therapy for Peyronie’s Disease,” European Urology 70, no. 5 (November 2016): 895–96. doi: 10.1016/j.eururo.2016.08.026.
CHAPTER 18 PENIS 911: EMERGENCIES INVOLVING THE PENIS
1 Sachit Sharma and Sabyasachi Panda, “Prolonged Priapism Following Single Dose Administration of Sildenafil: A Rare Case Report,” Urology Annals 1, no. 2 (July–December 2009).
2 Brian V. Le and Arthur L. Burnett, “Management of Priapism,” in T. S. Köhler and K. T. McVary (eds.), Contemporary Treatment of Erectile Dysfunction (Switzerland: Springer International Publishing, 2016), 326.
3 http://www.mayoclinic.org/diseases-conditions/priapism/symptoms-causes/dxc-20208950.
4 Le and Burnett, “Management of Priapism,” 330.
5 D. J. Ralph et al., “The Immediate Insertion of a Penile Prosthesis for Acute Ischaemic Priapism,” European Urology 56, no. 6 (2009): 1033–38.
6 Le and Burnett.
7 D. K. Montague et al., “American Urological Association Guideline on the Management of Priapism,” Journal of Urology 170, no. 4, pt. 1 (2003): 1318–24.
8 R. Barros et al., “Relationship Between Sexual Position and Severity of Penile Fracture,” International Journal of Impotence Research 29, no. 5 (September 2017): 207–9. doi: 10.1038/ijir.2017.24.
CHAPTER 19 LUMPS AND BUMPS: INFECTIONS, DISEASES, AND NORMAL VARIATIONS OF THE PENIS
1 who.int/mediacentre/factsheets/fs110/en/.
2 John R. Brill, “Diagnosis and Treatment of Urethritis in Men,” American Family Physician 81, no. 7 (April 1, 2010): 873–78.
3 Sharon M. Smith, Tajudeen Ogbara, and Robert H. K. Eng, “Involvement of Gardnerella Vaginalis in Urinary Tract Infections in Men,” Journal of Clinical Microbiology (June 1992): 1575–77.
4 http://www.health.harvard.edu/womens-health/bacterial-vaginosis-gardnerella-vaginitis.
5 https://www.cancer.org/cancer/cancer-causes/infectious-agents/hpv/hpv-and-cancer-info.html.
6 Jose M. Martin, Inmaculada Molina, Carlos Monteagudo, Nuria Marti, and Veronica Lopez, “Buschke-Lowenstein Tumor,” Journal of Dermatological Case Reports 2, no. 4 (December 27, 2008): 60–62.
7 http://www.onhealth.com/content/1/sexually_transmitted_disease_std.
8 http://www.healthline.com/health/std/syphilis#stages2.
9 L. Parrish, “Psoriasis: Symptoms, Treatments and Its Impact on Quality of Life,” British Journal of Community Nursing 17, no. 11 (2012): 524, 526, 528.
10 Joel M. H. Teichman, Jason Sea, Ian M. Thompson, and Dirk M. Elston, “Noninfectious Penile Lesions,” American Family Physician 81, no. 2 (January 15, 2010): 167–74.
11 Ibid.
12 Ibid.
13 Clarence William Brown, Medscape (February 13, 2014). Retrieved March 8, 2014.
14 G. S. Gerber, “Carcinoma in Situ of the Penis,” Journal of Urology 151, no. 4 (1994): 829–33.
15 Teichman et al., “Noninfectious Penile Lesions.”
16 NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) Penile Cancer Version 2.2016.
17 Surabhi Dayal and Priyadarshini Sahu, “Zoon Balanitis: A Comprehensive Review,” Indian Journal of Sexually Transmitted Diseases 37, no. 2 (July-December 2016): 29–38. doi: 10.4103/0253-7184.192128.
CHAPTER 20 THE MAKING AND UNMAKING OF A PENIS: VARIATIONS IN GENITALS AND GENDER IDENTITY
1 D. J. Summerton, J. McNally, A. J. Denny, and P. S. J. Malone, “Congenital Megaprepuce: An Emerging Condition—How to Recognize and Treat It,” BJU International 86, no. 4 (2000): 519–22.
2 https://www.niehs.nih.gov/health/topics/agents/endocrine/.
3 M. Fahmy, Congenital Anomalies of the Penis (Switzerland: Springer International Publishing, 2017), 265. doi: 10.1007/978-3-319-43310-3, 164.
4 Ibid.
5 L. Gaspari, D. R. Sampaio, F. Paris, F. Audran, M. Orsini, J. B. Neto, and C. Sultan, “High Prevalence of Micropenis in 2,710 Male Newborns from an Intensive-Use Pesticide Area of Northeastern Brazil,” International Journal of Andrology 35, no. 3 (2012): 253–64.
6 Fahmy, Congenital Anomalies of the Penis, 64.
7 Ibid., 265.
8 https://www.babycenter.com/0_brain-development-is-the-difference-between-boys-and-girls-a_10310673.bc.
9 W. C. Chung, G. J. De Vries, and D. F. Swaab, “Sexual Differentiation of the Bed Nucleus of the Stria Terminalis in Humans May Extend into Adulthood,” Journal of Neuroscience 22, no. 3 (February 1, 2002): 1027–33.
10 Ibid.
11 F. P. M. Kruijver, J. N. Zhou, C. W. Pool, M. A. Hofman, L. J. G. Gooren, and D. F. Swaab, “Male-to-Female Transsexuals Have Female Neuron Numbers in a Limbic Nucleus,” Journal of Clinical Endocrinology and Metabolism 85 (2000): 2034–41.
12 J. N. Zhou, M. A. Hofman, L. J. G. Gooren, and D. F. Swaab, “A Sex Difference in the Human Brain and Its Relation to Transsexuality,” Nature 378 (1995): 68–70.
13 A. Binet et al., “Should We Question Early Feminizing Genitoplasty for Patients with Congenital Adrenal Hyperplasia,” Journal of Pediatric Surgery 51 (2016): 465–8.
14 David Ralph, Nestor Gonzales-Cadavid, Vincenzo Mirone, Sava Perovic, Michael Sohn, Mustafa Usta, and Laurence Levine, “Trauma, Gender Reassignment, and Penile Augmentation,” Journal of Sexual Medicine 7 (2010): 1657–67.
15 S. C. Meier and C. M. Labuski, “Demographics of the Transgender Population,” in International Handbook on the Demography of Sexuality (Dordrecht, The Netherlands: Springer, 2013), 289–327; L. Conway and S. Winter, “How Many Trans* People Are There? A 2011 Update Incorporating New Data.” Available at: http://www.transgenderasia.org/paper-how-many-trans-people-arethere.htm. Accessed June 27, 2016.
16 Jordan D. Frey, Grace Poudrier, Michael V. Chiodo, and Alexes Hazen, “An Update on Genital Reconstruction Options for the Female-to-Male Transgender Patient: A Review of the Literature,” Plastic and Reconstructive Surgery 139, no. 3 (March 2017): 728–37.
17 Britt Colebunders, Sam Brondeel, Salvatore D’ArpaPiet Hoebeke, and Stan Monstrey, “An Update on the Surgical Treatment for Transgender Patients,” Sexual Medicine Reviews 5, no. 1 (2017): 103–9.
18 Ignacio Moncada, “Gender Reassignment Surgery from Female to Male,” Journal of Sexual Medicine 3, suppl. 2 (2006): 75–76.
19 Caitlyn Jenner, The Secrets of My Life (New York: Hachette, 2017).
20 The 2011 World Professional Association for Transgender Health Standards of Care, 7th version.
21 Peggy T. Cohen-Kettenis, Henriette A. Delemarre-van de Waal, and Louis J. G. Gooren, “The Treatment of Adolescent Transsexuals: Changing Insights,” Journal of Sexual Medicine 5 (2008): 1892–97.
22 Miroslav L. Djordjevic, Marta R. Bizic, Dragana Duisin, Mark-Bram Bouman, and Marlon Buncamper, “Reversal Surgery in Regretful Male-to-Female Transsexuals after Sex Reassignment Surgery,” Journal of Sexual Medicine 13 (2016): 1000e–1007e.
23 Colebunders et al., “An Update on the Surgical Treatment for Transgender Patients.”