Contents
Chapter 1 Historical Introduction to the Field of Controlled Drug Delivery
Anya M. Hillery and Allan S. Hoffman
Chapter 2 Principles of Controlled Release
Yvonne Perrie, Thomas Rades, and Kirsten Graeser
Chapter 3 Improving the Water Solubility of Poorly Soluble Drugs
Kohsaku Kawakami and Anya M. Hillery
Chapter 4 Overview of Epithelial Barriers
Floriane Laurent, Anya M. Hillery, and Randall Mrsny
Chapter 5 Nanotechnologies for Drug Delivery and Targeting: Opportunities and Obstacles
Alexander T. Florence and Daan J.A. Crommelin
Chapter 6 Long-Acting Injections and Implants
Jeremy C. Wright and James Matriano
Anya M. Hillery and David J. Brayden
Chapter 8 Buccal and Sublingual Drug Delivery
Marc B. Brown and Viralkumar F. Patel
Chapter 9 Transdermal Drug Delivery
Simon R. Corrie and Mark A.F. Kendall
Chapter 10 Nasal Drug Delivery
Per Gisle Djupesland and Anya M. Hillery
Chapter 11 Pulmonary Drug Delivery
Heidi M. Mansour, Paul B. Myrdal, Usir Younis, Priya Muralidharan, Anya M. Hillery, and Don Hayes, Jr.
Chapter 12 Drug Delivery to the Female Reproductive Tract
Patrick F. Kiser, Justin T. Clark, and Jonathan T. Su
Chapter 13 Ophthalmic Drug Delivery
Clive G. Wilson, Mariam Badawi, Anya M. Hillery, Shyamanga Borooah, Roly Megaw, and Baljean Dhillon
Ronald A. Siegel and Carmen Alvarez-Lorenzo
Chapter 15 Drug Delivery to the Central Nervous System
Anya M. Hillery
Chapter 16 Gene Delivery Systems
Kwang Suk Lim and Sung Wan Kim
Terry L. Bowersock and Suman M. Mahan
Chapter 18 Theranostic Nanoagents
Anthony S. Malamas and Zheng-Rong Lu
Chapter 19 Nanofabrication Techniques and Their Applications in Drug Delivery
Erica Schlesinger, Cade Fox, and Tejal Desai
Chapter 20 Rational Drug Discovery, Design, and Development
Haizhen A. Zhong, Osman F. Güner, and J. Phillip Bowen
Chapter 21 Commercial and Regulatory Development Considerations for Nanomedicines
Donna Cabral-Lilly and Lawrence D. Mayer
Chapter 22 Marketing Perspectives for Drug Delivery
Louise Rosenmayr-Templeton
David Needham
Anya M. Hillery and Kinam Park