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Index
Cover image
Title page
Table of Contents
Copyright
List of contributors
Preface
The Esophagus
Chapter 1: Esophageal Function Testing
Disorders of Esophageal Function
Diagnostic Tests for Esophageal Diseases
Summary
Acknowledgment
Chapter 2: Gastroesophageal Reflux Disease
Introduction
Operative Indications
Preoperative Evaluation
Surgical Treatment Options
Minimally Invasive Surgical Technique
Potential Operative Pitfalls
Postoperative Care
Common Postoperative Problems
Reoperative Fundoplication
Emerging Surgical Therapies for Gastroesophageal Reflux Disease
Chapter 3: Endoluminal Approaches to Gastroesophageal Reflux Disease
Introduction
Preoperative Considerations
Outcomes Assessment
Stretta
EsophyX
Future Methods
Summary
Chapter 4: The Management of Barrett's Esophagus
Introduction
Clinical Impact
Clinical Features
Treatment of Nondysplastic Barrett's Esophagus
Treatment of Dysplastic Barrett's Esophagus
Summary
Chapter 5: Endoscopic Treatment of Barrett's Esophagus
Introduction
Histologic Features of Barrett's Esophagus
Surveillance Algorithm for Barrett's Esophagus
Endoscopic Ablation Therapies
Endoscopic Mucosal Resection
Endoscopic Submucosal Dissection
Summary
Chapter 6: Paraesophageal Hernia
Definition
Clinical Manifestation
Pathophisiology
Therapy
Insights and Controversies in Paraesophageal Hernia Surgery
Results
Summary
Chapter 7: The Management of Pharyngeal Esophageal (Zenker's) Diverticula
Introduction
History
Etiology
Symptoms
Diagnosis
Indications for Surgery
Operative Technique
Postoperative Care
Results
Conclusion
Chapter 8: The Management of Achalasia of the Esophagus
Background
Diagnosis
Medical Therapy
Surgical Treatment
Further Discussion
Summary
Acknowledgment
Chapter 9: Disorders of Esophageal Motility
Introduction
Classes of Esophageal Motility Disorders
Chapter 10: The Management of Esophageal Carcinoma
Assessment of the Extent of Disease and Selection of Treatment Options
Treatment
Conclusions
Chapter 11: Neoadjuvant and Adjuvant Therapy of Esophageal Cancer
Introduction
Part I: Definition of Local-Regional Advanced Esophageal Cancer
Part II: Management of Local-Regional Advanced Esophageal Cancers
Summary
Chapter 12: Esophageal Stents
Indications
Historical Aspects
Stent Design
Clinical Evaluation and Technique
Complications
Special Considerations
Conclusions
Chapter 13: Esophageal Perforation
Initial Therapy
Management Decisions
Special Situations
The Stomach
Chapter 14: The Management of Benign Gastric Ulcer
Introduction
Etiology
Presentation and Diagnosis
Gastric Ulcer Types and Location
Surgical Technique
Reconstruction Techniques
Chapter 15: The Management of Duodenal Ulcers
Introduction
Medical Management of Duodenal Ulcers
Surgical Management of Duodenal Ulcers
Chapter 16: Zollinger-Ellison Syndrome
Introduction
Epidemiology
Pathogenesis
Clinical Presentation
Diagnosis
Management
Outcomes and Prognosis
Postoperative Surveillance
Areas of Controversies
Conclusion
Chapter 17: Mallory-Weiss Syndrome
History
Incidence, Pathophysiology, and Associated Conditions
Diagnoses and Outcomes
Treatment
Surgery
Summary
Chapter 18: Gastric Adenocarcinoma
Introduction
Surgery
D2 Lymphadenectomy Technique for Subtotal/Distal Gastrectomy
D2 Lymphadenectomy Technique for Total Gastrectomy
Neoadjuvant and Adjuvant Therapy
Follow-Up
Summary
Chapter 19: Gastrointestinal Stromal Tumors
Introduction
Pathologic Features
Epidemiology
Clinical Presentation
Diagnosis
Prognostic Factors
Therapy for Primary Disease
Therapy for Advanced Disease
Surveillance
Conclusion
Chapter 20: Morbid Obesity
Overview
Patient Selection
Operative Procedures
Outcomes and Complications
Small Bowel
Chapter 21: Small Bowel Obstruction
Overview
Evaluation and Diagnosis
Nonoperative Management
Operative Management
Chapter 22: The Management of Crohn's Disease of the Small Bowel
Overview
Medical Management
Indications for Surgical Management
Chapter 23: Strictureplasty in Crohn's Disease
Introduction
Overview
Strictureplasty Techniques
Results
Summary
Acknowledgment
Chapter 24: The Management of Small Bowel Tumors
Overview
Carcinoid/Neuroendocrine Tumors
Adenocarcinoma
Gastrointestinal Stromal Tumors
Non-Hodgkin's Lymphoma
Metastases
Benign Tumors
Chapter 25: The Management of Diverticulosis of the Small Bowel
Duodenal Diverticula
Jejuno-Ileal Diverticular Disease
Meckel's Diverticulum
Summary
Chapter 26: Motility Disorders of the Stomach and Small Bowel
Overview
Motility Disorders of the Stomach
Motility Disorders of the Small Intestine
Chapter 27: The Management of Short Bowel Syndrome
Introduction
Initial Management of the Abdominal Catastrophe That Leads to Short Bowel Syndrome
Indications for Surgical Management of Short Bowel Syndrome
Longitudinal Intestinal Lengthening and Tailoring
Serial Transverse Enteroplasty Procedure
Conclusion
Chapter 28: The Management of Enterocutaneous Fistulas
Overview
Definition and Etiology
Presentation
Physiologic Effect and Complications
Management
Surgical Management
Summary
Large Bowel
Chapter 29: Preoperative Bowel Preparation: Is it Really Necessary?
Overview
Historical Background
Mechanism of Action of Oral Antimicrobial Agents
Mechanical Bowel Preparation
Is Mechanical Bowel Preparation Still Warranted?
Summary
Chapter 30: The Management of Diverticular Disease of the Colon
Diverticulitis: Clinical Presentation
Management
Summary and Conclusion
Diverticular Bleeding
Chapter 31: The Management of Chronic Ulcerative Colitis
Introduction
Indications for Surgical Therapy
Surgical Options
Indications for a Subtotal Colectomy
Surgical Procedures
Conclusion
Chapter 32: The Management of Toxic Megacolon
Overview
Incidence and Etiology
Diagnosis
Therapy
Outcomes
Summary
Chapter 33: Crohn's Colitis
Introduction
Clinical Features
Diagnosis
Treatment
Stricture/Obstruction
Perforation, Fistulae, and Abscess
Massive Lower Gastrointestinal Bleeding
Severe Colitis/Fulminant Colitis/Toxic Megacolon
Extracolonic Manifestations of Crohn's Disease
Operations for Crohn's Colitis
Emergent Operation
Segmental Colectomy
Ileorectal Anastomosis
Total Proctocolectomy with End Ileostomy
Proctectomy
The Role of Laparoscopic and Robotic Surgery for Crohn's Colitis
Chapter 34: Ischemic Colitis
Overview
Anatomic Considerations
Clinical Presentation
Diagnosis
Treatment
Summary
Chapter 35: The Management of Clostridium Difficile Colitis
Overview
Clinical Manifestations
Diagnosis of Clostridium Difficile Infection
Medical Treatment
Surgery
Recurrent Infection
Clostridium Difficile Infection and Inflammatory Bowel Disease
Conclusion
Chapter 36: Large Bowel Obstruction
Overview
Obstructions as a Result of Cancer
Obstructions as a Result of Inflammation
Obstructions as a Result of Colonic Volvulus
Obstructions as a Result of Intussusception
Obstructions as a Result of Hernia
Obstructions as a Result of Ogilvie's Syndrome (PseudoObstruction)
Conclusion
Chapter 37: Colonic Stenting
Introduction
Technique
Complications
Outcomes
Summary
Chapter 38: Acute Colonic Pseudo-Obstruction (Ogilvie's Syndrome)
Introduction
Presentation and Diagnosis
Management
Summary
Chapter 39: The Management of Colonic Volvulus
Overview
Sigmoid Volvulus
Cecal Volvulus
Transverse Colon Volvulus
Splenic Flexure Volvulus
Chapter 40: Rectal Prolapse
Etiology and Presentation
Evaluation
Treatment
Summary
Chapter 41: The Management of Solitary Rectal Ulcer Syndrome
Clinical Findings
Diagnosis
Histologic Findings
Etiology
Treatment
Chapter 42: Surgical Management of Constipation
Etiology and Workup
Obstructed Defecation Syndrome
Stapled Transanal Rectal Resection
Slow-Transit Constipation
Antegrade Colonic Enemas
Sacral Nerve Stimulation
Ostomy Creation
Summary
Chapter 43: Radiation Injury to the Small and Large Bowel
Overview
Radiation Dose Tolerance to the Small Intestine and Rectum
Pathophysiology of Radiation to the Intestinal Tract
Management of Radiation Enteritis
Management of Radiation Proctitis
Prevention of Radiation Enteritis and Proctitis
Chapter 44: Hereditary Polyposis Syndromes
Introduction
Adenomatous Polyposis Syndromes
Genetics
Surgical Therapy
Medical Therapy
Extracolonic Disease
Hamartomatous Polyposis Types
Conclusion
Acknowledgment
Chapter 45: Colon Cancer
Background and Epidemiology
Screening Recommendations
Presentation, Diagnosis, and Workup
Surgical Resection and Staging
Open Versus Laparoscopic Colectomy
Challenging and Complicated Cases
Adjuvant Treatment
Surveillance and Follow-Up
Chapter 46: The Management of Rectal Cancer
Introduction
Diagnosis
Treatment Approach by Stage
Surgical Therapy
Chapter 47: Tumors of the Anal Canal
General Considerations
Squamous Neoplasms
Adenocarcinoma
Melanoma
Neuroendocrine Tumors
Mesenchymal Tumors
Malignant Lymphoma
Chapter 48: The Use of Positron Emission Tomographic Scanning in the Management of Colorectal Cancer
Introduction
Background
Detection of Colorectal Cancer
Screening for Colorectal Cancer
Tumor Staging and Treatment Planning
Assessment of Tumor Response
Recurrent Colorectal Cancer
Summary
Chapter 49: The Use of Neoadjuvant and Adjuvant Treatment for Colorectal Cancer
Overview
Staging
Adjuvant Therapy for Colon Cancer
Neoadjuvant and Adjuvant Therapy for Rectal Cancer
Chapter 50: The Management of Colorectal Polyps
Overview
Histopathology and Natural History of Polyps
Colonoscopic Polypectomy
Approach to the Malignant Polyp
Chapter 51: Management of Peritoneal Surface Malignancy
Introduction
Pseudomyxoma Peritonei and Peritoneal Metastases From Appendiceal Malignancy
Peritoneal Metastases of Colorectal Origin
Diffuse Malignant Peritoneal Mesothelioma
Peritoneal Metastases From Epithelial Ovarian Cancer
Peritoneal Metastases From Gastric Cancer
Chapter 52: The Management of Acute Appendicitis
Overview
Historical Perspective
Anatomy and Pathophysiology
Patient Presentation and Diagnosis
Management of Acute Appendicitis
Timing of Surgery
Management of Nonperforated Appendicitis
Management of Perforated Appendicitis
Special Patient Situations
Chapter 53: Hemorrhoids
Anatomy
Etiology and Pathophysiology
Incidence
External Hemorrhoids
Internal Hemorrhoids
Special Situations
Chapter 54: Anal Fissure
Treatment
Acknowledgment
Chapter 55: Anorectal Abscess and Fistula
Introduction
Abscess
Fistulas
Primary Fistulotomy
Setons
Advancement Flaps
Fibrin Sealant
Fistula Plug
Ligation of Intersphincteric Fistula Tract
Choice of Procedure
Conclusion
Chapter 56: Anorectal Stricture
Definition
Causes
Clinical Presentation
Diagnosis
Nonoperative Management
Operative Management
Summary
Chapter 57: The Management of Pruritus Ani
Introduction
Etiology
Patient Evaluation
Treatment
Summary
Chapter 58: Surgical Treatment of Fecal Incontinence
Overlapping SpHincteroplasty
Sacral Nerve Stimulation
Injectables
Artificial Bowel Sphincter
Other
Chapter 59: The Management of Rectovaginal Fistula
Introduction
Causes
Clinical Manifestation
Classification of Rectovaginal Fistulae
Preoperative Preparation
Surgical Management
Treatment Guidelines
Special Considerations
Acknowledgments
Chapter 60: The Management of Condyloma Acuminata
Presentation and Evaluation
Therapy
Giant Condyloma Acuminata
Chapter 61: The Management of Pilonidal Disease
Pilonidal Disease: Common and Challenging
Etiology and Characteristics
A Changing Paradigm
Diagnosis and Differential Diagnosis
Acute Pilonidal Abscess Management
Chronic Pilonidal Sinus
Nonsurgical Approaches
Surgical Approaches
Surgical Pitfalls
Who Should Perform Surgical Procedures on Pilonidal Disease
Cancer and Pilonidal Disease
Summary
Chapter 62: Lower Gastrointestinal Bleeding
Definition
Etiology
Diagnostic Assessment and Therapy
Summary
The Liver
Chapter 63: Cystic Disease of the Liver
Overview and Clinical Presentation
Diagnostic Evaluation
Imaging Modalities
Simple Cysts
Polycystic Liver Disease
Neoplastic Cysts
Traumatic Cysts
Pyogenic Liver Abscess
Chapter 64: The Management of Echinococcal Cyst Disease of the Liver
Pathology and Classification
Presentation and Diagnosis
Treatment
Results
Chapter 65: Cavernous Hepatic Hemangioma
Pathophysiology and Clinical Presentation
Diagnosis
Management
Infantile Hepatic Hemangioma
Summary
Chapter 66: The Management of Benign Liver Lesions
Diagnosis and Imaging of Benign Liver Lesions
Surgery for Benign Liver Lesions
Summary
Chapter 67: The Management of Malignant Liver Tumors
Overview
Hepatocellular Carcinoma
Fibrolamellar Hepatocellular Carcinoma
Intrahepatic Cholangiocarcinoma
Preoperative Assessment
Operative Approach to Resection of Primary Liver Malignancies
Chapter 68: Treatment For Hepatocellular Carcinoma: Resection Versus Transplantation
Introduction
Evaluation
Imaging
Staging
Treatment
Chapter 69: Radiofrequency Ablation of Hepatic Metastases from Colorectal Cancer
Overview
Indications and Preoperative Assessment
Technical Considerations
Complications
Monitoring and Follow-Up
Results and Response Rates
Newer Technologies
Conclusion
Chapter 70: The Management of Hepatic Abscess
Overview
Pyogenic Hepatic Abscess
Amebic Hepatic Abscess
Fungal Hepatic Abscess
Chapter 71: Transarterial Chemoembolization for Liver Metastases
Introduction
History
Technique
Palliation for Other Liver Tumors
Contraindications to Transarterial Chemoembolization
Complications
Drug-Eluting Beads
Current Evidence
Portal Hypertension
Chapter 72: Portal Hypertension: The Role of Shunting Procedures
Management of Acute Variceal Hemorrhage
Endoscopic Diagnosis and Therapy
Luminal Tamponade
Radiologic Interventions
Rebleeding Prophylaxis
Surgical Shunts
Comparison of Transjugular Intrahepatic Portacaval Shunt with Shunt Surgery
Summary
Chapter 73: The Role of Liver Transplantation in Portal Hypertension
Etiologies of Portal Hypertension
Pathophysiology of Portal Hypertension
Medical Management of Portal Hypertension
Surgical and Radiologic Management of Portal Hypertension
Liver Transplantation
Chapter 74: Endoscopic Therapy for Esophageal Variceal Hemorrhage
Overview
Endoscopic Therapy
Results
Summary
Chapter 75: Transjugular Intrahepatic Portosystemic Shunt
Overview
Indications
Technique
Clinical Outcomes
Summary
Chapter 76: The Management of Refractory Ascites
Introduction
Pathophysiology
Chapter 77: The Management of Hepatic Encephalopathy
Overview
Pathophysiology
Classification and Managementof Hepatic Encephalopathy
Chapter 78: The Management of Budd-Chiari Syndrome
Overview
Presentation and Diagnosis
Treatment
Medical Therapy
Surgical Therapy
Summary
Gallbladder and Biliary Tree
Chapter 79: The Management of Asymptomatic (Silent) Gallstones
Overview
Epidemiology and Natural History
Prophylactic Cholecystectomy
Incidental Cholecystectomy
Special Populations
Chapter 80: Acute Cholecystitis
Overview
Clinical Presentation and Evaluation
Differential Diagnosis
Management
Laparoscopic Cholecystectomy
Open Cholecystectomy
New Developments
Complications
Chapter 81: The Management of Common Bile Duct Stones
Overview
Clinical Laboratory Findings
Imaging Workup
Management
Summary
Chapter 82: Acute Cholangitis
Overview
Epidemiology
Pathogenesis
Clinical Presentation
Diagnosis
Therapy
Chapter 83: Benign Biliary Strictures
Iatrogenic Biliary Injuries
Other Benign Biliary Strictures
Chapter 84: Cystic Disorders of the Bile Ducts
Overview
Classification
Etiology
Epidemiology
Diagnosis and Preoperative Evaluation
Management
Prognosis
Chapter 85: Primary Sclerosing Cholangitis
Demographics
Etiology
Associated Diseases and Complications
Natural History and Prognostic Models
Presentation
Diagnosis
Therapy
Summary
Chapter 86: Management of Cholangiocarcinoma
Overview
Clinical Presentation
Diagnosis
Preoperative Evaluation
Surgical Treatment and Outcomes
Palliation
Summary
Chapter 87: Gallbladder Cancer
Overview
Natural History, Biology, and the Role of Surgical Treatment
Staging
Radiologic Evaluation
Management
Palliative Care
Chapter 88: Gallstone Ileus
Pathogenesis
Diagnosis
Management
Chapter 89: Obstructive Jaundice: Endoscopic Therapy
Introduction
Endoscopic Therapies for Obstructive Jaundice
Benign Biliary Obstruction
Malignant Obstruction
The Pancreas
Chapter 90: Acute Pancreatitis
Assessment of Severity
Complications of Pancreatitis
Management of Patients with Acute Pancreatitis
Management of Complications of Acute Pancreatitis
Summary
Chapter 91: The Management of Gallstone Pancreatitis
Overview
Presentation and Diagnosis
Treatment
Chapter 92: Pancreas Divisum and other Variants of Dominant Dorsal Duct Anatomy
Introduction
Pancreatic Embryologic Development
Clinical Significance
Diagnostic Strategies
Treatment
Conclusion
Chapter 93: Pancreatic Necrosis
Introduction
Definitions and Diagnosis
Role of Prophylactic Antibiotics
Timing of Surgical Intervention
Therapeutic Intervention for Pancreatic Necrosis
Summary
Chapter 94: The Management of Pancreatic Pseudocyst
Overview
Pathophysiology
Presentation
Diagnostic Evaluation
Management
Conclusion
Chapter 95: Pancreatic Ductal Disruptions Leading to Pancreatic Fistula, Pancreatic Ascites, or Pancreatic Pleural Effusion
Introduction
Etiology and Complications
Clinical Presentation and Diagnosis
Management and Treatment
Conclusion
Chapter 96: The Management of Chronic Pancreatitis
Introduction
Definition and Types of Chronic Pancreatitis
Diagnosis and Severity Classification
Medical Management
Endotherapy
Surgical Treatment
Surgical Drainage and Resection Techniques
Summary
Chapter 97: Periampullary Carcinoma
Overview
Periampullary Cancer Types
Clinical Presentation and Physical Findings
Laboratory Studies
Surgical Therapy
Surgical Outcomes
Adjuvant and Neoadjuvant Therapy and Survival
Chapter 98: Vascular Reconstruction During the Whipple Operation
Overview
Rationale for PV/SMV Resection
Preoperative Imaging
Surgical Anatomy of the Superior Mesenteric Vein
Surgical Technique
Arterial Reconstruction
Summary
Chapter 99: Palliative Therapy for Pancreatic Cancer
Introduction
Indications for Palliative Interventions
Palliative Surgical Interventions
Outcomes after Surgical Palliation
Palliative Resection Versus Palliative Bypass
Palliative Chemotherapy and Chemoradiation
Conclusions
Chapter 100: Neoadjuvant and Adjuvant Therapy of Pancreatic Cancer
Introduction
Adjuvant Therapy
Neoadjuvant Therapy
Future Directions
Chapter 101: Unusual Pancreatic Tumors
Overview
Nonneoplastic Pancreatic Cysts
Pancreatic Cystic Neoplasms
Rare Solid Pancreatic Tumors
Autoimmune Pancreatitis
Pancreatic Tumors/Masses Not of Pancreatic Origin
Cancer Metastastic to the Pancreas From Other Sites
Chapter 102: Intraductal Papillary Mucinous Neoplasms of the Pancreas
Preoperative Workup
Indications for Resection
Operative Strategy
Prognosis and Follow-Up
Chapter 103: The Management of Pancreatic Islet Cell Tumors Excluding Gastrinomas
Overview
Diagnosis
Functional Tumors
Chapter 104: Transplantation of the Pancreas
Introduction
Whole-Organ Pancreas Transplantation
Complications
Results
Risk/Benefit Considerations
The Spleen
Chapter 105: Hematologic Indications for Splenectomy
Overview of Splenic Structure and Function
Erythrocyte Disorders
Platelet Disorders
Preoperative Considerations
Laparoscopic Splenectomy
Postoperative Considerations
Conclusion
Chapter 106: Cysts, Tumors, and Abscesses of the Spleen
Cysts
Tumors
Abscesses
Overwhelming Postsplenectomy Sepsis
Chapter 107: Splenic Salvage Procedures: Therapeutic Options
Nonoperative Management
Operative Splenic Salvage
Recommendations
Hernia
Chapter 108: Inguinal Hernia
Overview
Diagnosis
Inguinal Hernia Repair
Chronic Postinguinal Herniorrhaphy Pain
Chapter 109: Recurrent Inguinal Hernia
Introduction
Prevention
Anatomy
Diagnosis
Patient Preparation
Anesthesia
Repair Options
Complications
Summary
Chapter 110: Incisional, Epigastric, and Umbilical Hernias
Incisional Hernias (Ventral Hernias)
Umbilical Hernias
Epigastric Hernia
Approach to the Repair of Ventral Hernias
Follow-Up
Conclusion
Chapter 111: The Management of Semilunar Line, Lumbar, and Obturator Herniation
Introduction
Semilunar Line (Spigelian) Herniation
Lumbar Herniation
Obturator Herniation
Summary
Chapter 112: Athletic Pubalgia: The “Sports Hernia”
Introduction
Background
Anatomy, Pathophysiology, and Differential Diagnosis
Management
Summary
Chapter 113: Abdominal Wall Reconstruction
Anatomy
Patient Evaluation
Approach to Repair
Prosthetic Materials
Conclusions
The Breast
Chapter 114: Management of Benign Breast Disease
Evaluation of Benign Breast Complaints
Breast Masses
Fibroadenomas
Breast Cysts
Breast Pain
Nipple Discharge
Breast Infection
Abnormal Screening Mammograms
Summary
Chapter 115: Screening for Breast Cancer
Overview
Screening Recommendations
Screening Modalities
High-Risk Screening
Other Imaging Modalities
Future
Chapter 116: The Role of Stereotactic Breast Biopsy in the Management of Breast Disease
Introduction
History
Certification
Patient Selection, Indications, and Contraindications
The Fundamentals
The Procedure
Challenging Clinical Scenarios
Pathologic Correlation
Conclusions and Future Directions
Chapter 117: Molecular Targets in Breast Cancer
Molecular Profiling
Estrogen Receptor Signaling Pathways
Growth Factor Recptor Pathways and Down Stream Pathways
PI3K/AKT Pathway
Angiogenesis
DNA Repair Pathways
Chapter 118: Breast Cancer: Surgical Management
Introduction
Diagnosis and Workup
Treatment
Adjuvant Therapy
Prophylactic Surgery
Summary
Chapter 119: Ablative Therapies in Benign and Malignant Breast Disease
Overview
Cryoablation
Radiofrequency Ablation
Chapter 120: Lymphatic Mapping and Sentinel Lymphadenectomy
Introduction
Indications and Contraindications for Sentinel Lymph Node Biopsy
Technical Aspects
Special Considerations
Alternatives to Axillary Lymph Node Dissection for Positive Sentinel Lymph Nodes
Complications
Future Directions
Conclusion
Chapter 121: The Management of the Axilla in Breast Cancer
Overview
Clinically Node-Negative Invasive Breast Cancer
Clinically Node-Positive Invasive Breast Cancer
Axillary Management for Ductal Carcinoma in Situ
Axillary Management in Pregnant Patients
Axillary Management in the Elderly
Axillary Management in Male Breast Cancer
Positive Axillary Nodes with an Occult Primary Tumor
Axillary Management after Neoadjuvant Chemotherapy
Management after Prior Axillary Surgery
Management of Axillary Tumor Recurrence
Axillary Radiation after Axillary Dissection
Alternatives to Axillary Surgery
Technical Aspects of Axillary Lymph Node Dissection
Chapter 122: Inflammatory Breast Carcinoma
Introduction
Clinical Presentation
Diagnosis and Staging
Treatment
Prognosis and Follow-Up
Chapter 123: Ductal and Lobular Carcinoma in Situ of the Breast
Ductal Carcinoma in Situ
Lobular Carcinoma in situ
Chapter 124: Advances in Neoadjuvant and Adjuvant Therapy for Breast Cancer
Overview
Neoadjuvant Systemic Therapy
Adjuvant Therapy
Summary
Chapter 125: The Management of Recurrent and Disseminated Breast Cancer
Introduction
Relapse Patterns and Definitions
Therapeutic Principles and Strategies
Chapter 126: Male Breast Cancer
Overview
Risk Factors
Presentation
Diagnosis
Treatment
Prognosis
Chapter 127: Breast Reconstruction Following Mastectomy: Indications, Techniques, and Results
Indications
Reconstructive Techniques
Endocrine Glands
Chapter 128: Adrenal Incidentaloma
Overview/Clinical Problem
Imaging
Rapid Office Biochemical Evaluation (Summary)
Clinical EvAluation
Preoperative Preparation
Operative Technique and Postoperative Care
Chapter 129: The Management of Adrenal Cortical Tumors
Overview
Incidentaloma
Functional Hormone-Secreting Tumors
Adrenocortical Carcinoma
Adrenal Metastases
Laparoscopic Adrenalectomy
Summary
Chapter 130: The Management of Pheochromocytoma
Overview
Clinical Presentation
Diagnosis
Preoperative Management
Intraoperative Management
Operative Technique
Postoperative Management
Palliative Therapy
Chapter 131: The Management of Thyroid Nodules
History
Physical Examination
Laboratory Assessment
Radiology Assessment
Surgical Considerations
Intraoperative Frozen Section
Summary
Chapter 132: Nontoxic Goiter
Overview
Pathogenesis
Clinical Features
Evaluation
Indications for Treatment
Treatment Modalities
Postoperative Care
Chapter 133: The Management of Thyroiditis
Overview
Chronic Lymphocytic Thyroiditis
Subacute Lymphocytic Thyroiditis
Subacute Granulomatous Thyroiditis
Acute Suppurative Thyroiditis
Invasive Fibrous Thyroiditis
Drug-Induced Thyroiditis
Chapter 134: Hyperthyroidism
Introduction
Assessment and Diagnosis
Nonsurgical Treatment
Surgical Indications and Contraindications
Surgical Preparation
Surgical Options
Surgical Anatomy
Surgical Technique
Postoperative Management
Complications
Conclusion
Chapter 135: Surgical Approach to Thyroid Cancer
Background
Diagnosis and Surgical Management
Surgical Aproach
Recurrent Laryngeal Nerve Monitoring
Lymph Node Dissection
Operative Outcomes
Postoperative Management
Chapter 136: Primary Hyperparathyroidism
Background and Epidemiology
Pathophysiology, Presentation, and Diagnosis
Indications for Surgery
Localization
Minimally Invasive Parathyroidectomy with Intraoperative Parathyroid Hormone Monitoring
Bilateral Neck Exploration
Outcomes and Follow-Up
Conclusion
Chapter 137: Persistent and Recurrent Hyperparathyroidism
Introduction
Diagnosis of Persistent or Recurrent Hyperparathyroidism
Indications for Reoperative Parathyroidectomy
Preoperative Considerations
Preoperative Evaluation
Preoperative Localization Studies
Operative Technique
Postoperative Management
Conclusion
Chapter 138: Secondary and Tertiary Hyperparathyroidism
Overview
Pathophysiology
Clinical Manifestations of Secondary and Tertiary Hyperparathyroidism
Medical Management
Surgical Management
Postoperative Management
Chapter 139: Metabolic Changes Following Bariatric Surgery
Metabolic Consequences of Obesity
Metabolic Improvements after Weight Loss Surgery
Metabolic Surgery and Future Directions
Chapter 140: Glycemic Control and Cardiovascular Disease Risk Reduction after Bariatric Surgery
Introduction
Bariatric Procedures
Conclusions
Skin and Soft Tissue
Chapter 141: Nonmelanoma Skin Cancers
Risk Factors and Precurser Lesions
Clinical Evaluation of Basal Cell and Squamous Cell Cancers
Dermatfibrosarcoma Protuberans
Cutaneous T-Cell Lymphoma
Basal Cell Nevus Syndrome
Bowen's Disease
Merkle Cell Carcinoma
Angiosarcoma
Adenexal Tumors of the Skin
Conculsion
Acknowledgments
Chapter 142: The Management of Cutaneous Melanoma
Overview
Biopsy Techniques
Treatment of Primary Lesion
Treatment of Regional Nodes
In-Transit Disease
Metastatic Disease
Follow-Up
Management of Recurrent Disease
Conclusion
Chapter 143: The Management of Soft Tissue Sarcoma
Overview
Etiology
Grading
Treatment
Imaging
Histology-Specific Treatment
Extremity Soft Tissue Sarcoma
Retroperitoneal Soft Tissue Sarcoma
Breast Sarcoma
Desmoid Fibromatosis
Metastatic Disease
Summary
Chapter 144: Evaluation of the Isolated Neck Mass
Overview
Differential Diagnosis
Workup
Surgical Considerations
Chapter 145: Hand Infections
Introduction
Microbiology
Finger Infections
Hand Infections
Necrotizing Fasciitis of the Upper Extremity
Osteomyelitis
Chapter 146: Nerve Injury and Repair
Introduction
General Principles
Preoperative Management
Operative Technique
Postoperative Management
Summary
Chapter 147: Extremity Gas Gangrene
Introduction
Bacteriology
Diagnosis
Treatment
Outcome
Chapter 148: Necrotizing Skin and Soft Tissue Infections
Overview
Pathophysiology
Diagnosis
Microbiology
Treatment
Reconstruction
Complications
Conclusion
Chest Wall, Mediastinum, Trachea
Chapter 149: The Management of Primary Chest Wall Tumors
Overview
Diagnosis
Benign Bony and Cartilaginous Tumors
Malignant Bony and Cartilaginous Tumors
Benign Soft Tissue Tumors
Malignant Soft Tissue Tumors
Surgical Treatment of Chest Wall Tumors
Options for Chest Wall Reconstruction
Summary
Chapter 150: Mediastinal Masses
Introduction
Clinical Presentation and Diagnosis
Conclusion
Chapter 151: Primary Tumors of the Thymus
Anatomy
Pathology
Evaluation
Staging
Principles of Therapy
Operative Management
Summary
Chapter 152: The Management of Tracheal Stenosis
Timing of Therapy
Indications for Resection
Factors to Consider for Tracheal Resection
Airway Management
Tracheal Resection and Reconstruction
Results
Chapter 153: The Management of Acquired Esophageal Respiratory Tract Fistula
Overview
Benign Esophageal Respiratory Fistulas
Treatment of Benign Fistulas
Malignant Esophageal Respiratory Tract Fistula
Summary
Chapter 154: Repair of Pectus Excavatum
Evaluation of the Patient with Pectus Excavatum
Open Repair
Minimally Invasive Pectus Excavatum Repair (Nuss Procedure)
Complications of Minimally Invasive Repair
Outcome of Pectus Excavatum Repair
Vascular Surgery
Chapter 155: Open Repair of Abdominal Aortic Aneurysms
Overview
Indications for Repair
Preoperative Planning
Surgical Repair
Complications
Conclusion
Chapter 156: Endovascular Treatment of Abdominal Aortic Aneurysm
Introduction
Preoperative Considerations
Technical Details of the Procedure
Postoperative Care and Follow-Up
Complications
Summary
New Devices on the Horizon
Chapter 157: The Management of Ruptured Abdominal Aortic Aneurysm
Introduction
Diagnosis and Evaluation
Treatment
Discussion
Summary
Chapter 158: Abdominal Aortic Aneurysm and Unexpected Abdominal Pathology
Overview
Elective Abdominal Aortic Aneurysm Repair and Asymptomatic Abdominal Disease
Gastrointestinal Malignancies
Emergent Abdominal Aortic Aneurysm Repair and Concomitant Disease
Emergent Laparotomy for Symptomatic Abdominal Pathology with Incidental Asymptomatic Abdominal Aortic Aneurysm
Elective Laparotomy for Abdominal Pathology with Incidental Asymptomatic Abdominal Aortic Aneurysm
Summary
Chapter 159: The Management of Thoracic and Thoracoabdominal Aortic Aneurysms
Introduction
Indications for Surgery
Preoperative Risk Assessment
Open Surgical Management
Endovascular Surgical Management
Alternative Approaches
Chapter 160: The Management of Acute Aortic Dissections
Overview
Classification
Presentation and Diagnosis
Management
Surgical Management of Stanford a Dissections
Surgical Results with Acute Type a Dissections
Management of Acute Type B Dissections
Chapter 161: Carotid Endarterectomy
Overview
Clinical Presentation
Indications
Carotid Endarterectomy: Operative Technique
Complications
Recurrent Carotid Stenosis
Combined Carotid Endarterectomy–Coronary Artery Bypass
Chapter 162: The Management of Recurrent Carotid Artery Stenosis
Incidence of Restenosis
Timing of Restenosis and Pathogenesis
Risk Reduction
Diagnosis of Restenosis
Indications for Reintervention
Intervention for Recurrent Carotid Stenosis
Reoperative Carotid Endarterectomy
Carotid Angioplasty and Stenting
Summary
Chapter 163: Balloon Angioplasty and Stents in Carotid Artery Occlusive Disease
Background
Technical Considerations in Performance of Carotid Artery Stenting
Design of Carotid Stent Systems
Periprocedural Management
Summary and Perspective
Chapter 164: The Management of Aneurysms of the Extracranial Carotid and Vertebral Arteries
Introduction
Carotid Artery Aneurysms
Vertebral Artery Aneurysms
Chapter 165: Brachiocephalic Reconstruction
Introduction
Clinical Presentation
Diagnostic Evaluation
Treatment
Anatomic (Direct) Revascularization
ExtraAnatomic (Indirect) Revascularization
Arterial Transposition
Endovascular Treatment
Innominate Artery Interventions
Summary
Chapter 166: Upper Extremity Arterial Occlusive Disease
Overview
Etiology
Evaluation
Management
Summary
Chapter 167: Aortoiliac Occlusive Disease
Introduction
Initial Evaluation and Indications for Intervention
Direct Surgical Revascularization
Aortobifemoral Bypass
Iliofemoral Bypass
ExtraAnatomic Bypass
Femorofemoral Bypass
Axillobifemoral Bypass
Other Surgical Revascularization Options
Complications of Surgical Revascularization
Results of Surgical Revascularization
Endovascular Interventions
Results of Endovascular Interventions
Summary
Chapter 168: Femoropopliteal Occlusive Disease
Introduction
Evaluation
Treatment
Discussion
Summary
Chapter 169: Tibioperoneal Arterial Occlusive Disease
Patient Assessment
Selection of Intervention
Surgical Bypass
Endovascular Revascularization
Other Technologies
Postintervention Management and Surveillance
Complications
Future Treatment: Cell-Based Therapies
Conclusion
Chapter 170: Profunda Femoris Reconstruction
Profunda Femoris Artery
Basic Anatomy
Operative Role
Isolated Profundaplasty
Operative Approaches
Endovascular Therapy
Conclusion
Chapter 171: Femoral and Popliteal Artery Aneurysms
Overview
Degenerative Femoral Aneurysms
Iatrogenic Femoral Pseudoaneurysms
Popliteal Aneurysms
Chapter 172: The Treatment of Claudication
The Initial Evaluation of the Patient with Suspected Claudication
Initial Management of the Patient with Claudication: Management of Limb Symptoms
Initial Management of the Patient with Claudication: Management of Generalized Atherosclerosis
Follow-Up after Initiation of Medical Management and Selection of Patients for Intervention
Treatment of the Arterial Occlusive Lesions That Cause Claudication
Summary
Chapter 173: Pseudoaneurysms and Arteriovenous Fistulas
PSEUdoaneurysms
Arteriovenous Fistula
Chapter 174: Axillofemoral Bypass
Introduction
Indications
Preoperative Evaluation
Techniques
Graft Configurations
Results
Complications
Postoperative Management
Conclusions
Chapter 175: The Management of Peripheral Arterial Emboli
Overview
Classification, Site, and Source of Embolism
Pathophysiology
Clinical Presentation
Diagnostic Examination
Management
Outcomes/Results
Chapter 176: Acute Peripheral Arterial and Bypass Graft Occlusion: Thrombolytic Therapy
Overview
Patient Presentation and Workup
Conclusion
Chapter 177: Atherosclerotic Renal Artery Disease
Introduction
Incidence
Natural History of Renal Artery Stenosis
Treatment
Summary
Chapter 178: Raynaud's Syndrome
Overview
Pathogenesis
Diagnosis and Presentation
Treatment
Conclusions
Chapter 179: Thoracic Outlet Syndromes
Overview
Anatomy of the Thoracic Outlet
Arterial Compression
Venous Compression (Paget-Schroetter Syndrome)
Nerve Compression
Transaxillary Approach
Chapter 180: The Diabetic Foot
Introduction
Pathophysiology
Presentation
Treatment
Conclusion
Disclaimer
Chapter 181: Gangrene of the Foot
Overview
Risk Factors and Epidemiology
Evaluation
Management
Summary
Chapter 182: Buerger's Disease (Thromboangiitis Obliterans)
Introduction
Clinical Presentation
Diagnosis
Treatment
Prognosis
Summary
Chapter 183: Acute Mesenteric Ischemia
Overview
Anatomy and Collateralization
Pathophysiology
Clinical Presentation and Diagnosis
Treatment
Conclusion
Chapter 184: The Management of Chronic Mesenteric Ischemia
Arterial Disease
Reconstruction Options
Extent of Visceral Artery Reconstruction
Outcome of Open Revascularization
Chapter 185: Hemodialysis Access Surgery
Introduction
Historical Notes
National Practices and Guidelines
Preoperative Evaluation
Operative Techniques
Complications and Management
Conclusions
Chapter 186: Venous Thromboembolism: Prevention, Diagnosis, and Treatment
Introduction
Impact
Risk Factors
Prevention and Prophylaxis
Diagnosis
Screening of Asymptomatic Patients
Treatment
Conclusion
Chapter 187: Deep Venous Thrombosis
Risk Factors
Diagnosis
Therapy
Special Considerations
Chapter 188: Vena Cava Filters
Introduction
Indications and Contraindications for Inferior Vena Cava Filter Placement and Retrieval
Filter Selection
Technique
Filter Retrieval
Complications
Discussion
Chapter 189: The Prevention of Venous Thromboembolism
Epidemiology
Risk Factors
Venous Thromboembolism Prophylaxis
Venous Thromboembolism Diagnosis
Venous Thromboembolism Treatment
Inferior Vena Cava Filter
Catheter-Directed Thrombolytic Therapy
Systemic Thrombolysis
Complications
Summary
Chapter 190: Lymphedema
Diagnosis
Treatment
Summary
Trauma and Emergency Care
Chapter 191: Initial Assessment and Resuscitation of the Trauma Patient
Initial Assessment and Resuscitation of the Trauma Patient
Primary Survey
Resuscitation and Monitoring
Secondary Survey
Next Steps
Chapter 192: Airway Management in the Trauma Patient
Initial Airway Assessment and Therapy
Rapid Sequence Induction and Intubation
Endotracheal Intubation
Supraglottic Airway Devices
Awake Fiberoptic Intubation
Airway Management Decision Making
Surgical Airway
Chapter 193: The Surgeon's Use of Ultrasound in Thoracoabdominal Trauma
Focused Assessment for the Sonographic Evaluation of the Trauma Patient
Traumatic Hemothorax
Pneumothorax
Sternal Fracture
Special Situations
Using Ultrasound to Assess Intravascular Volume Status and Cardiac Function
Summary
New Horizons in Point of Care Ultrasound
Chapter 194: Emergency Department Thoracotomy
Overview
Indications
Procedural Techniques
Outcomes
Chapter 195: The Management of Traumatic Brain Injury
Evaluation
Surgical Treatment
Nonsurgical Management
Management of Mild to Moderate Head Injuries
Comments
Chapter 196: Chest Wall Trauma, Hemothorax, and Pneumothorax
Initial Evaluation
Specific Injuries
Tube Thoracostomy
Chapter 197: Abdominal Trauma
Initial Management
Topography and Clinical Anatomy
Physical Examination
Diagnostic Studies
Penetrating Abdominal Injuries and the Hemodynamically Stable and Unstable Condition
Exploratory Laparotomy in Trauma
Summary
Chapter 198: Penetrating Abdominal Trauma
Historical Perspective
Anatomic Definitions
Mechanism of Injury
Initial Management
Diagnostic Adjuncts
Indications for Operative Intervention and Practical Algorithms
Operating Room Conduct and Management of Specific Injuries
Summary
Chapter 199: Diaphragmatic Injuries
Introduction
Epidemiology
Anatomy
Diagnosis
Acute Management
Special Situations
Management of the Chronic Posttraumatic Hernia
Morbidity and Mortality
Chapter 200: The Management of Liver Injuries
Introduction
Blunt Hepatic Trauma
Interventional Radiology
Penetrating Hepatic Trauma: Clinical Decision Making
Operative Techniques for Hepatic Trauma
Museum Pieces
Conclusion
Chapter 201: Pancreatic and Duodenal Injuries and Current Surgical Therapies
Epidemiology and Management Priorities
Kinematics (Mechanism of Injury)
Duodenum
Pancreas
Chapter 202: Injuries to the Small and Large Bowel
Mechanism of Injury
Diagnosis
Surgical Management
Chapter 203: The Management of Rectal Injuries
Overview
Diagnosis
Anatomic Location of Injury and Injury Grading
Surgical Management
Morbidity and Complications Management
Conclusion and Algorithm
Chapter 204: Injury to the Spleen
Overview
Diagnosis
Nonoperative Management
Penetrating Splenic Injury
Operative Management
Immunizations
Chapter 205: Retroperitoneal Injuries: Kidney and Ureter
Kidney
Ureter
Chapter 206: Damage Control Operation
Basic Principles
Physiology and Indications
Phase 1: Initial Operation on the Abdomen or Other Body Cavities
Phase 2: Resuscitation
Phase 3: Definitive Surgical Management
Evidence for Effectiveness of DCO
Chapter 207: Urologic Complications of Pelvic Fracture
Bladder Injury
Urethral Injury
Conclusions
Chapter 208: Facial Trauma: Evaluation and Management
Overview
Emergent Treatment and Evaluation
Soft Tissue Injuries and Management
Bony Injuries and Management
Extensive Injuries and Management
Conclusion
Chapter 209: Penetrating Neck Trauma
Introduction
Anatomy
Initial Evaluation/Management
Management of Specific Injuries
Chapter 210: Blunt Cardiac Injury
Introduction
Incidence
Mechanism of Injury
Diagnosis
Treatment
Chapter 211: Abdominal Compartment Syndrome and Management of the Open Abdomen
Pathophysiology of Abdominal Hypertension
Recognition of Abdominal Compartment Syndrome
Measurement of Intraabdominal Pressure
Treatment of Abdominal Compartment Syndrome
Unplanned Reoperation
Temporary Abdominal Wall Closures
Abdominal Wall Reconstruction
Failure to Achieve Primary Closure
Types of Definitive Abdominal Closures
Special Situations in Damage Control Surgery
Conclusion
Chapter 212: Blood Transfusion Therapy in Trauma
Introduction
Blood Components
Autologous Blood Transfusions
Acute Coagulopathy
Massive Transfusion and Massive Transfusion Protocols
Coagulation Testing in the Trauma Patient
Hemostatic Adjuncts
Complications From Transfusion Therapy
Novel Anticoagulants
New Directions
Chapter 213: Coagulation Issues and the Trauma Patient
Overview
Etiology and Natural History
Current Concepts of Coagulation
Treatment of the Bleeding Trauma Patient: Optimal Use of Component Therapy
Military Experience
Summary
Chapter 214: The Abdomen That Will not Close
Stage 1: Prosthetic Insertion and Attempt at Delayed Primary Closure
Stage 2: Staged Split-Thickness Skin Grafting for Planned Ventral Hernia
Stage 3: Definitive Reconstruction with a Modification of the Components Separation Technique
Chapter 215: The Management of Vascular Injuries
Overview
Initial Evaluation and Management
Body Regions and Typical Vascular Injuries
Summary
Chapter 216: Endovascular Management of Arterial Injury
Extracranial Cerebrovascular Injury
Upper Extremity Injury
Aortoiliac Injury
Abdominal Aorta and Iliac Vasculature
Iliac Arteries
Lower Extremity Injury
Adjunctive Techniques
Chapter 217: The Management of Extremity Compartment Syndrome
Pathophysiology
Etiology
Diagnosis
Treatment: Compartment Decompression
Postoperative Management
Chapter 218: Burn Wound Management
Overview
The Burn Wound
Management of Superficial Burns
Management of Deep Burns
Excision of Burn Wounds
Closure of Excised Burn Wounds
Complications of Burn Wound Healing
Chapter 219: Practical Management of the Burn Patient
Introduction
Physiologic Changes with Burn Injury
Phase One Management: Initial Evaluation and Resuscitation
Phase Two Management: Wound Excision and Biologic Closure
Burn Critical Care
Phase Three Management: Definitive Wound Closure
Phase Four Management: Reconstruction and Reintegration
Conclusion
Chapter 220: Cold Injury, Frostbite, and Hypothermia
Overview
Nonfreezing Cold Injuries
Freezing Cold Injuries
Classification of Frostbite
Prevention of Frostbite
Initial Field Treatment of Frostbite
Medical Therapy
Thrombolytic, Vasodilator, and Prostacyclin Therapy
Surgical Intervention
Chronic Changes of Frostbite
Accidental Hypothermia
Classification of Hypothermia and Symptoms
Physiologic Effects of Hypothermia
Diagnosis and Treatment
Intraoperative Hypothermia
Therapeutic Hypothermia
Chapter 221: Electrical and Lightning Injury
Epidemiology
Electricity Basics
Physics and Pathophysiology of Electrical Injury
Management
Preoperative and Postoperative Care
Chapter 222: Fluids and Electrolytes
Introduction
Fluid Compartments and Osmolality
Daily Requirements and Choice of Maintenance Fluids
Assessment of Fluid Status and Choice of Replacement Fluids
Diagnosis and Treatment of Electrolyte Disorders
Chapter 223: Preoperative Assessment of the Older Patient: Frailty
Overview
Older Surgical Patients
Frailty
Frailty, Comorbidity, and Disability
Frailty and Surgical Risk Prediction
Alternative Measures of Frailty and Surgical Outcomes
Sarcopenia and Surgery
Logisitics of Preoperative Measurement of Frailty
Conclusion
Chapter 224: Preoperative Preparation of the Surgical Patient
Introduction
Oral Intake Guidelines
Preoperative Testing
Comorbidities
Medication Management
Summary
Chapter 225: Is a Nasogastric Tube Necessary after Alimentary Tract Surgery?
Chapter 226: Surgical Site Infections
Overview
Definition
Risk Factors
Prevention
Treatment
Summary
Chapter 227: The Management of Intra-Abdominal Infections
Introduction
Definitions
Diagnostics
Intra-abdominal Infections Following Abdominal Trauma or Surgery
Management of Intra-abdominal Infections
Source Control: Operation Versus Percutaneous Drainage Alone
Chapter 228: Occupational Exposure to Human Immunodeficiency Virus and other Bloodborne Pathogens
Progress in the Field
Occupational Exposure to Bloodborne Pathogens
Chapter 229: Antifungal Therapy in the Surgical Patient
Introduction
Antifungal Agents
Specific Infections
Conclusions
Chapter 230: Measuring Outcomes in Surgery
Introduction
Donabedian Model of Quality
Variation in Outcomes
Current Measures of Outcomes
Integrating Outcome Measurement Into the Current Practice of Surgery
The Importance of Outcome Measurement in Research
Conclusion
Chapter 231: Comparative Effectiveness Research in Surgery
Introduction
What is Comparative Effectiveness Research?
Effectiveness Versus Efficacy
Which Treatment?
Which Patients?
Which Outcome?
How is Comparative Effectiveness Research Done?
Comparative Effectiveness Research in the National and International Spotlight
Controversy
Future Directions
Surgical Critical Care
Chapter 232: Surgical Palliative Care
Chapter 233: Cardiovascular Pharmacology
Overview
Tachyarrhythmias
Bradydysrhythmias
Control of Cardiac and Systemic Vascular Performance
Treatment of Systemic Hypertension
Pharmacologic Reduction of Perioperative Cardiac Risk
Chapter 234: Glucose Control in the Postoperative Period
Introduction
Indications
Techniques
Results
Summary
Chapter 235: Postoperative Respiratory Failure
Introduction
Acute Respiratory Failure
Classification and Epidemiology
ARF Treatment: Noninvasive Ventilation
ARF Treatment: Intubation
Treatment: VAP Prevention
Treatment: Mechanical Ventilation
Modes of Mechanical Ventilation
Advanced Modes of Mechanical Ventilation in the ICU
Mechanical Ventilation Strategies for ALI and ARDS
Adjuncts to Mechanical Ventilation in Patients with ARDS and Severe Hypoxemia
Incremental Approach to the Management of Severe ARDS
Weaning and Liberation From Mechanical Ventilation
Tracheostomy
Chapter 236: Ventilator-Associated Pneumonia
Introduction
Diagnosis
Treatment
Summary
Chapter 237: Extracorporeal Membrane Oxygenation for Respiratory Failure in Adults
Introduction
The Extracorporeal Membrane Oxygenation System
Management
Troubleshooting the ECMO
Weaning and Lung Recovery
Discussion
Chapter 238: Tracheostomy
Introduction
Indications and Contraindications
Summary
Chapter 239: Acute Kidney Failure
Overview
Definitions
Diagnosis of Acute Kidney Injury
Radiologic Imaging
Medication Review
Differential Diagnosis
Renal Protective Strategies
Treatment
Prognosis
Chapter 240: Electrolyte Disorders
Overview
Sodium
Potassium
Magnesium
Calcium and Phosphate
Summary
Chapter 241: Acid-Base Problems
Normal Acid-Base Metabolism
Metabolic Acidosis
Respiratory Acidosis
Metabolic Alkaloses
Respiratory Alkalosis
Chapter 242: Central Line–Associated Bloodstream Infections
Introduction
Prevention
Diagnosis and Treatment
Summary
Chapter 243: The Septic Response
Definition
Epidemiology
Pathophysiology
Diagnosis
Treatment
Supportive Care
Summary
Chapter 244: Multiple Organ Dysfunction and Failure
History and Pathophysiology
Clinical Presentation and Organ System Management
Pulmonary Dysfunction—Acute Lung Injury
Acute Kidney Injury
Hepatic Dysfunction
Central Nervous System Dysfunction—Delirium
Endocrine and Metabolic Dysfunction
Therapeutic Strategies—Nutrition
Patient-Centered Outcomes and Palliative Care
Summary
Chapter 245: Antibiotics for Critically Ill Patients
Diagnosis of Infection and Empiric Therapy
Principles of Antibiotic Therapy
Specific Considerations
Multidrug-Resistant Organisms
Antibiotic Toxicities
Avoidance of Toxicity: Adjustment of Antibiotic Dosage
Chapter 246: Endocrine Changes in Critical Illness
Overview
Adrenal Insufficiency
Hyperglycemia
Thyroid Dysfunction
Drug-Induced Endocrine Disorders in the Intensive Care Unit
Chapter 247: Nutritional Support in the Critically Ill
Overview
Metabolic Response to Stress and Nutritional Requirements during Critical Illness
Early Enteral Nutrition
Total Parenteral Nutrition
Immunonutrition
Special Circumstances: the Obese Critically Ill Patient
Chapter 248: Coagulopathy in the Critically Ill Patient
A Model of Hemostasis
An Initial Approach to the Critically Ill Patient with Bleeding
Hemostatic Testing in the Critically Ill Patient
Platelet Disorders
Inherited Quantitative Platelet Disorders
Inherited Qualitative Platelet Disorders
Inherited Coagulation Disorders
Acquired Coagulation Disorders
Low-Molecular-Weight Heparin
Warfarin
Direct Thrombin Inhibitors
Liver Disease
Acquired Factor Inhibitors
Cardiac Surgery–Associated Bleeding
Vessel Wall Disorders
Minimally Invasive Surgery
Chapter 249: Laparoscopic Cholecystectomy
Introduction
Indications for Cholecystectomy
Imaging Diagnosis
Complicated Gallstone Disease
Biliary Dyskinesia/Chronic Acalculous Cholecystitis
Gallbladder Polyps
Laparoscopic Cholecystectomy Technique
The Difficult Cholecystectomy
Alternative Approaches: Single-Incision Laparoscopic and Notes Cholecystectomy
Complications
Summary
Chapter 250: Laparoscopic Common Bile Duct Exploration
Introduction
Intraoperative Evaluation of Common Bile Duct Stones
Techniques
After Cholecystectomy
Efficacy of Laparoscopic Common Bile Duct Exploration
Alternative Management
Summary
Chapter 251: Laparoscopic 360-Degree Fundoplication
Background
Symptoms and Complications
Medical Therapy
Diagnostic Workup
Surgical Therapy
Technique
Postoperative Care
Complications
Outcomes
Conclusion
Chapter 252: Laparoscopic Appendectomy
Introduction
Pathophysiology
Diagnosis
Indications
Techniques
Results
Special Considerations
Summary
Chapter 253: Laparoscopic Inguinal Herniorrhaphy
Overview
Evaluating the Patient
Relevant Anatomy
Indications and Contraindications
Preparing the Patient
Totally Extraperitoneal
Transabdominal Preperitoneal
Management of Complicated Hernia
After Surgery
Complications
Summary
Acknowledgment
Chapter 254: Laparoscopic Repair of Recurrent Inguinal Hernias
Overview
Indications and Choice of the Repair
Outcomes
Chapter 255: Laparoscopic Ventral Hernia Repair
Introduction
Indications
Preoperative Workup
Operative Technique
Postoperative Care
Special Circumstances
Complications
Outcomes
Chapter 256: Laparoscopic Repair of Peristomal Hernias
Background
Indications and Contraindications
Preoperative Planning
Surgery
Operative Technique
Postoperative Management
Complications
Results
Conclusions
Chapter 257: Laparoscopic Splenectomy
Overview
Indications and Contraindications
Preoperative Preparation
Techniques
Right Lateral Approach
Anterior Approach
Laparoscopic Hand-Assisted
Postoperative Care
Complications
Results
Summary
Chapter 258: Laparoscopic Gastric Surgery
Overview
Indications and Rationale for Laparoscopic Gastrectomy
Contraindications
Preoperative Workup and Preparation
Surgical Principles for Laparoscopic Gastrectomy
Pitfalls during a Laparoscopic Gastrectomy
Extent of Lymphadenectomy
Omentectomy and Bursectomy
Technique of Laparoscopic Gastrectomy
Techniques of Reconstruction
Special Considerations
Chapter 259: Laparoscopic Management of Crohn's Disease
Overview
Stomach and Duodenum
Small Bowel
Colon and Rectum
Perineum
Summary
Chapter 260: Laparoscopic Colon and Rectal Surgery
Background
Operative Principles and Technical Pearls
Complications and Learning Curve of Laparoscopic Colectomy
Chapter 261: Minimally Invasive Esophagectomy
Overview
Indications
Preoperative Preparation
Minimally Invasive Ivor Lewis Esophagectomy
Laparoscopic Transhiatal Esophagectomy
Thoracoscopic and Laparoscopic Esophagectomy with Cervical Anastomosis
Postoperative Care
Results
Summary
Chapter 262: Laparoscopic Treatment of Esophageal Motility Disorders
Introduction
Laparoscopic Heller Myotomy and Partial Fundoplication for Achalasia
Revisional Surgery after Heller Myotomy
Laparoscopic Treatment of End-Stage Achalasia
Laparoscopic Treatment of Epiphrenic Diverticula
Summary
Chapter 263: Laparoscopic Adrenalectomy
Introduction
Indications
Techniques
Complications
Postoperative Care
Outcomes
The Future: Even LESS Invasive Surgery
Chapter 264: Minimally Invasive Parathyroidectomy
Preoperative Parathyroid Localization
Intraoperative Adjuncts
Surgical Approach
Postoperative Management
Chapter 265: Laparoscopic Liver Resection
Overview
Preoperative Evaluation
Anesthesia and Intraoperative Monitoring
Operative Techniques
Operative Metrics
Conclusion
Chapter 266: Staging Laparoscopy for Gastrointestinal Cancer
Overview
General Technique
Esophageal Cancer
Gastric Adenocarcinoma
Colorectal Liver Metastasis and Hepatobiliary Primary Tumors
Pancreatic and Periampullary Adenocarcinomas
Lymphoproliferative Diseases
Natural Orifice Transluminal Endoscopic Surgery
Summary
Chapter 267: Laparoscopic Pancreas Surgery
Laparoscopic Whipple
Laparoscopic Distal Pancreatectomy
Laparoscopic Central Pancreatectomy
Laparoscopic Total Pancreatectomy with Islet Autotransplantation
Older and High-Risk Patients
Conclusion
Acknowledgments
Chapter 268: Laparoscopic Bypass for Pancreatic Cancer
Background
Gastric Outlet Obstruction
Laparoscopic Biliary Bypass Procedures
Conclusions
Chapter 269: Laparoscopic Management of Pancreatic Pseudocyst
Overview
Clinical Features
Preoperative Workup
Operative Indications
Procedure Selection
Preoperative Planning
Laparoscopic Cystgastrostomy
Laparoscopic Cystjejunostomy
Postoperative Care
Outcomes and Complications
Brief Comment on Walled-Off Necrosis
Chapter 270: Video-Assisted Thoracic Surgery
Introduction
Indications for Video-Assisted Thoracic Surgery and Patient Selection
Surgical Setup and Equipment
Basic Technique and Emergency Conversion to Thoracotomy
Summary
Chapter 271: Laparoscopic Surgery for Morbid Obesity
Preoperative Evaluation
Preparing the Patient in the Operating Room
Techniques
Postoperative Management
Outcomes and Complications
Endoscopic Approaches to the Management of Obesity
Comments
Chapter 272: Laparoscopic Donor Nephrectomy
Overview
Evaluation of the Live Kidney Donor
Contraindications
Operative Approach
Postoperative Management
Risks
Conclusion
Chapter 273: Laparoendoscopic Single-Site Surgery as An Evolving Surgical Approach
Training and Learning Curve
Devices and Instruments
Transumbilical Approach
Nephrectomy
Cholecystectomy
Bariatric Surgery
Colectomy
Urgent Indications
Urologic Surgery
Gynecologic Surgery
Robotic Single-Port Approach
Cost Considerations
Consent Issues
Strategies for Successful Incorporation of the Single-Port Technique
Conclusions
Chapter 274: NOTES: What Is Currently Possible?
Overview
Treatment and Methods
NOTES: What Will be Possible in the Near Future?
Index
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