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Index
Cover page
Halftitle page
Series page
Title page
Copyright page
Contents
List of illustrations
1 Introduction
2 The fundamentals
Carbon: an elemental socialite
Naming compounds and identifying their structure
Stereochemistry
Functional groups
Intermolecular and intramolecular interactions
3 The synthesis and analysis of organic compounds
Devising a synthesis
Retrosynthesis
Carrying out and monitoring a reaction
Changing the conditions of a reaction
Isolation and purification of a reaction product
Structural analysis
Reaction mechanisms
4 The chemistry of life
Amino acids and proteins
Nucleotides and nucleic acids
Other biosynthetic processes
Function of proteins
Function of nucleic acids
Chemical evolution
Evolution of life’s biopolymers
Making use of proteins and nucleic acids
5 Pharmaceuticals and medicinal chemistry
The pathfinder years
The development of rational drug design
Identification of a drug target
Drug testing and bioassays
Identification of lead compounds
Structure–activity relationships and pharmacophores
Drug design and drug optimization
Drug candidates and patenting
Chemical and process development
Preclinical trials and formulation
Clinical trials and regulatory affairs
The future
Veterinary drugs
Drugs of abuse
6 Pesticides
Insecticides
Insecticides: organochlorine agents
Insecticides: methylcarbamates and organophosphates
Insecticides: pyrethrins and pyrethroids
Insecticides: neonicotinoids
Future insecticides
Fungicides
Herbicides
7 The chemistry of the senses
The chemistry of vision
The chemistry of scent
The chemistry of taste
8 Polymers, plastics, and textiles
Addition polymers
Condensation polymers
Epoxy cements and superglues
Health issues
Environmental, ecological, and economic issues
Recycling/depolymerization
Biodegradable plastics
Bioplastics
Recent research in plastics and polymers
9 Nanochemistry
Carbon allotropes
Nanotubes
Rotaxanes
Nanoparticles
Nanotechnology and DNA
Examples of nanodevices and nanomachines
Nanotechnology: safety and toxicology
Further reading
Index
Scientific Revolution
The History of Medicine
Nuclear Power
Nuclear Weapons
Social Media
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